Predictive factors and prevalence of microalbuminuria in HIV-infected patients: a cross-sectional analysis

Falasca, Katia; Di Nicola, Marta; Porfilio, Italo; Ucciferri, Claudio; Schiaroli, Elisabetta; Gabrielli, Chiara; Francisci, Daniela; Vecchiet, Jacopo

doi:10.1186/s12882-017-0672-9

BMC Nephrology

Table 2 Mean and standard deviation of metabolic parameters

From: Predictive factors and prevalence of microalbuminuria in HIV-infected patients: a cross-sectional analysis

	Equal		Improved		Worse		Time^a	Subgroup^b	Interaction^c
	T0	T48	T0	T48	T0	T48	Time^a	Subgroup^b	Interaction^c
Systolic blood pressure, mmHg	125.0 ± 14.9	125.4 ± 14.0	122.8 ± 15.4	124.6 ± 16.1	121.4 ± 17.3	123.1 ± 15.8	0.097	0.432	0.534
Diastolic blood pressure, mmHg	78.0 ± 9.6	78.5 ± 12.1	77.2 ± 8.9	78.8 ± 10.2	75.8 ± 9.9	77.0 ± 9.7	0.114	0.557	0.684
Total cholesterol, mg/dL	190.8 ± 43.2	191.6 ± 42.4	182.7 ± 47.7	203.3 ± 54.3	187.3 ± 51.8	204.9 ± 44.9	0.141	0.646	0.020
Triglycerides, mg/dL	159.5 ± 90.2	167.2 ± 145.9	146.5 ± 81.6	142.0 ± 74.6	136.1 ± 70.4	142.4 ± 98.2	0.958	0.384	0.980
LDL-cholesterol, mg/dL	111.1 ± 37.1	114.0 ± 33.6	103.7 ± 41.4	125.9 ± 38.9	119.1 ± 47.3	115.4 ± 35.8	0.009	0.872	0.007
Fasting glucose, mg/dL	92.5 ± 21.3	91.7 ± 30.3	91.5 ± 20.7	81.9 ± 9.2	96.4 ± 25.6	89.3 ± 15.8	0.176	0.117	0.257
CD4, %	30.2 ± 9.8	37.1 ± 54.3	28.1 ± 10.9	29.2 ± 10.5	32.1 ± 6.3	33.2 ± 7.9	0.514	0.581	0.748
CD4+, cell/μL	651.4 ± 295.8	688.0 ± 294.7	659.5 ± 344.0	767.1 ± 398.1	663.0 ± 281.2	755.4 ± 323.4	0.001	0.675	0.376
CD4/CD8 ratio	0.8 ± 0.5	0.9 ± 0.4	0.8 ± 0.5	0.8 ± 0.4	0.9 ± 0.3	1.0 ± 0.4	0.208	0.699	0.178
Creatinine, mg/dL	0.9 ± 0.2	0.9 ± 0.3	0.8 ± 0.2	0.9 ± 0.2	0.8 ± 0.1	0.8 ± 0.1	0.600	0.359	0.503
Uric acid, mg/dL	5.3 ± 2.0	5.3 ± 1.5	5.1 ± 1.2	5.1 ± 1.5	5.3 ± 2.3	4.8 ± 0.9	0.656	0.608	0.733
MDRD glomerular filtration rate, mL/min/1.73 m2	100.7 ± 24.4	101.6 ± 23.4	89.0 ± 55.2	90.5 ± 27.6	95.7 ± 17.3	91.9 ± 16.5	0.991	0.728	0.870
Albuminemia, g/dl	4.4 ± 0.4	4.4 ± 0.3	4.3 ± 0.4	4.4 ± 0.4	4.4 ± 0.3	4.5 ± 0.3	0.217	0.487	0.725
GOT/GPT ratio	0.8 ± 0.3	0.9 ± 0.3	0.9 ± 0.4	0.9 ± 0.3	1.0 ± 0.3	1.2 ± 0.7	0.004	0.021	0.060
Cystatin C, mg/L	0.8 ± 0.2	0.9 ± 0.2	0.8 ± 0.2	0.9 ± 0.2	0.7 ± 0.1	0.8 ± 0.1	<0.001	0.612	0.250

^aProbability that values are influenced by time. For each variable, the difference has been tested between the mean of the T0 and the mean of the T48, independently of subgroup
^bProbability that values are influenced by the change of state of microalbuminuria. For each variable, the difference has been tested between the means of the subgroups, independently of time
^cProbability that the effect of the treatment time is different in the three subgroups (equal, improved and worse)
p values in bold suggest significant values

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