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Table 2 Correlation between CD34+ glomerular capillaries and histopathological parameters of glomeruli in GL and TIL model mice

From: Local CD34-positive capillaries decrease in mouse models of kidney disease associating with the severity of glomerular and tubulointerstitial lesions

Parameters

Indices for glomerular histopathology

Glo. Size (μm2)

Cell number/glo.

Glo. damage score

B220+B-cells/Glo.

CD3+T-cells/Glo.

Iba1+macrophages/Glo.

CD34+ capillaries/Glo.

GL model

BXSB/MpJ

3850 ± 116.35b#

35.91 ± 1.40b#

18.25 ± 9.8b#

0.26 ± 0.03b#

0.12 ± 0.04b#

0.13 ± 0.02b#

17.29 ± 0.87b#

BXSB/MpJ-Yaa

6771.94 ± 446.32a#acd**

71.85 ± 3.30a#acd**

206.25 ± 36.29a#

1.63 ± 0.57a#acd*

1.79 ± 0.45a#acd*

3.57 ± 0.40a#acd*

9.68 ± 1.25a#ac*

TIL model

Control kidney

3161.13 ± 0.53b**

31.88 ± 0.53b**

0

0.18 ± 0.04b*

0.13 ± 0.02b*

0.07 ± 0.01b*

13.3 ± 0.42b*

UUO kidney

3010 ± 64.50b**

31.31 ± 0.47b**

0

0.22 ± 0.03b*

0.08 ± 0.01b*

0.03 ± 0.0b*

12.56 ± 0.19

  1. Values = mean ± SE. #: Significant difference from the control in the same disease group, Mann–Whitney U test (p < 0.05). *Significant difference from the other groups, Kruskal-Wallis test followed by Scheffe’s method (* p < 0.05, ** p < 0.01). N = 4. Glo.: glomerular; Pod: podocyte; GLs: glomerular lesions; TILs: tubulointerstitial lesions
  2. a, b, cand ddenotes BXSB/MpJ, BXSB/MpJ-Yaa, Control and UUO kidney, respectively