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Table 2 Baseline characteristics of study patients according to cardiovascular disease (CVD)

From: Associations of genetic variants of endothelin with cardiovascular complications in patients with renal failure

 

CVD (n = 118)

No CVD (n = 72)

p value

Gender, male, n (%)

74 (62.7%)

29 (40.3%)

0.003

Age (years)

67 ± 13

60 ± 12

<0.001

Dialysis vintage (years)

4.3 ± 3.8

5.5 ± 6.7

0.111

Current smoking (%)

20 (16.9%)

5 (6.9%)

0.050

Diabetes, n (%)

73 (61.9%)

17 (23.6%)

<0.001

ERI (unit/week/kg/Hb)

8.5 ± 6.7

8.0 ± 4.1

0.600

Hemoglobin (g/dl)

10.7 ± 1.2

10.7 ± 1.1

0.980

Albumin (g/dl)

3.9 ± 0.4

4.1 ± 0.4

0.005

Ferritin (mg/dl)

418 ± 401

458 ± 736

0.635

Iron (mg/dl)

65 ± 24

68 ± 33

0.571

TIBC (mg/dl)

236 ± 47

242 ± 54

0.441

Serum i-PTH (pg/mL)

277 ± 363

422 ± 354

0.012

Kt/V

1.44 ± 0.26

1.60 ± 0.31

0.001

Cause of ESRD, n (%)

  

<0.001

 Hypertension

16 (13.5%)

18 (25.0%)

 

 Diabetes

67 (56.8%)

17 (23.6%)

 

 GN

14 (11.9%)

22 (30.6%)

 

 CHF

8 (6.8%)

0 (0%)

 

 Others

13 (11.0%)

15 (20.8%)

 
  1. CHF congestive heart failure, ERI erythropoietin resistance index, ESRD end-stage renal disease, GN glomerulonephritis, iPTH parathyroid hormone, Kt/V dialysis adequacy, TIBC total iron-binding capacity. p values of <0.05 are shown in bold