Table 1 Characteristics of study population with and without rapid decline of renal function
Characteristics | Total population (n = 948) | With rapid decline of renal function (n = 223) | Without rapid decline of renal function (n = 725) | P-value |
|---|---|---|---|---|
Age (year) | 60(52–69) | 61(53–71) | 60(52–69) | 0.033 |
Men (%) | 423(44.6) | 80(35.9) | 343(47.3) | 0.003 |
BMI (kg/m2) | 25.32(23.37–27.76) | 25.46(23.88–28.13) | 25.27(23.19–27.64) | 0.089 |
SBP (mmHg) | 129(117–141) | 130(119–140) | 128(116–141) | 0.701 |
DBP (mmHg) | 77(70–84) | 79(70–83) | 77(70–84) | 0.221 |
CAD (%) | 107(11.3) | 27(12.1) | 80(11.0) | 0.658 |
Hypertension (%) | 471(49.7) | 125(56.1) | 346(47.7) | 0.030 |
Diabetes (%) | 246(25.9) | 77(34.5) | 169(23.3) | 0.001 |
cfPWV (m/s) | 10.7(9.3–12.6) | 10.8(9.4–12.8) | 10.6(9.3–12.6) | 0.404 |
cAIx (%) | 27(20–33) | 28(22–33) | 27(20–33) | 0.090 |
TG (mmol/L) | 1.47(1.08–2.11) | 1.49(1.14–2.17) | 1.47(1.07–2.10) | 0.328 |
HDL-c (mmol/L) | 1.34(1.13–1.55) | 1.31(1.11–1.50) | 1.35(1.14–1.59) | 0.064 |
LDL-c (mmol/L) | 2.89(2.42–3.29) | 2.91(2.53–3.24) | 2.88(2.40–3.31) | 0.712 |
FBG (mmol/L) | 4.97(4.52–5.48) | 4.97(4.41–5.66) | 4.97(4.54–5.46) | 0.893 |
PBG (mmol/L) | 6.54(5.28–8.46) | 6.89(5.52–10.12) | 6.40(5.26–8.25) | 0.001 |
Homocysteine (μmol/L) | 16.75(13.60–20.70) | 17.30(14.70–20.90) | 16.30(13.20–20.65) | 0.006 |
NT-proBNP (pg/ml) | 38.41(18.40–73.54) | 41.55(22.50–84.77) | 37.30(17.05–70.30) | 0.017 |
Hs-cTnT (pg/ml) | 4.00(3.00–8.19) | 4.19(3.00–9.13) | 4.00(3.00–7.92) | 0.359 |
Baseline GFR (mL/min/1.73m2) | 87.79(79.27–96.89) | 102.01(89.94–113.83) | 85.19(77.89–92.32) | <0.001 |
Follow-up GFR (mL/min/1.73m2) | 80.10(72.02–87.89) | 76.47(67.75–83.84) | 81.19(73.27–88.85) | <0.001 |
△GFR/year (mL/min/1.73 m2/year) | 1.46(0.42–2.91) | 4.40(3.45–6.38) | 1.01(0.08–1.81) | <0.001 |