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Table 5 Factors associated with CRRT mortality

From: The role of the specialized team in the operation of continuous renal replacement therapy: a single-center experience

 

Univariated analysis

Mulivariated analysis

Variables

HR

95% CI

P

HR

95% CI

P

Age, yr

1.003

0.995–1.012

0.458

   

Male, %

1.035

0.809–1.324

0.784

   

BMI, kg/m2

0.989

0.960–1.020

0.491

   

CRRT team intervention

0.798

0.629–1.014

0.064

   

SOFA score

1.326

1.274–1.380

<0.001

1.255

1.198–1.314

<0.001

CRRT initiation time, day

1.008

0.998–1.018

0.099

1.057

1.034–1.080

<0.001

Actually delivered dose, mL/kg/hr

1.020

1.006–1.035

0.004

   

CRRT down time per day, hr

0.883

0.827–0.942

<0.001

   

Number of filter used

0.942

0.913–0.972

<0.001

   

Total CRRT operation duration, day

0.968

0.945–0.990

0.006

   

Total protein, g/dL

0.625

0.553–0.706

<0.001

0.817

0.667–1.000

0.505

Albumin, g/dL

0.440

0.362–0.534

<0.001

0.708

0.516–0.971

0.032

BUN, mg/dL

0.996

0.992–1.000

0.044

   

Cr, mg/dL

0.892

0.848–0.938

<0.001

   

Na, mmol/L

1.014

0.999–1.028

0.064

   

TCO2, mmol/L

0.970

0.951–0.989

0.003

   

PT, INR

2.088

1.693–2.576

<0.001

1.328

1.092–1.616

0.005

  1. Adjusted factors: Age, sex, CRRT team intervention, CRRT initiation time, CRRT duration, number of filter used, actually delivered dose, total protein, serum albumin, serum sodium level, prothrombin time and SOFA score
  2. Abbreviations: BMI body mass index; CRRT continuous renal replacement therapy; SOFA sequential organ failure score; Cr creatinine; Na sodium; TCO2 total carbon dioxide; PT prothrombin time