Fig. 3

Representative findings of tubules in MCNS patients in the AKI group. a-b Staining of vimentin (a) or Ki67 (b) in consecutive sections. Mesangium and vessels are positive for vimentin, but approximately normally shaped tubules are negative for vimentin. Small groups of vimentin-positive tubules exhibiting mainly simplified morphology are observed in the vicinity of glomeruli (a). + indicate the distal tubule from a morphological aspect (a). Most Ki67-positive cells are observed in vimentin-positive tubules (b) (g: glomeruli; original magnification ×200).