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Table 1 Comparison of the clinical characteristics in patients with and without AKI

From: Unique proximal tubular cell injury and the development of acute kidney injury in adult patients with minimal change nephrotic syndrome

Characteristics

All

AKI

Non-AKI

No of patients

37

13

24

Age (years)

44.3 ± 19.4

50.8 ± 21.0

40.8 ± 17.9

Gender (% male)

59.4

69.2

54.1

History of HT (%)

24.3

30.7

20.8

Hypotension (%)a

5.4

0

8.3

Systolic BP (mmHg)

133.2 ± 13.3

140.4 ± 12.2

129.4 ± 12.5*

Diastolic BP (mmHg)

79.6 ± 10.8

83.8 ± 9.1

77.5 ± 11.1

Presence of CKD (%)

8.1

15.3

4.1

Diuretics use (%)

64.8

76.9

58.3

Proteinuria (g/gCr)

9.01 ± 3.53

9.09 ± 3.97

8.97 ± 3.36

Hematuria (%)

16.2

15.3

4.1

uNAG (IU/gCr)

25.7 ± 15.4

33.0 ± 19.7

21.7 ± 11.1*

uA1MG (mg/gCr)

53.9 ± 31.1

72.9 ± 38.1

43.6 ± 31.5*

serum Cr (mg/dl)

1.15 ± 0.57

1.72 ± 0.62

0.84 ± 0.18***

eGFR (ml/min/1.73 m2)

62.4 ± 27.2

35.3 ± 18.1

76.2 ± 19.8***

Serum albumin (g/dl)

1.5 ± 0.4

1.4 ± 0.2

1.6 ± 0.4

Time to CR (days)

26.4 ± 26.7

43.0 ± 36.0

17.4 ± 14.0**

Serum Cr at CR (mg/dl)

0.93 ± 0.53

1.20 ± 0.83

0.78 ± 0.16*

  1. Data expressed as the mean ± SD or proportions
  2. HT hypertension, BP blood pressure, CKD chronic kidney disease, uNAG urinary N-acetyl-β-D-glucosaminidase, uA1MG urinary alpha1-microglobulin, Cr creatinine, eGFR estimated glomerular filtration rate, CR complete remission. aHypotension at kidney biopsy
  3. * P < 0.05, ** P < 0.01 and *** P < 0.001 vs. AKI group were indicated