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Table 3 Comparison of renal pathological data in patients with and without AKI

From: Unique proximal tubular cell injury and the development of acute kidney injury in adult patients with minimal change nephrotic syndrome

Kidney biopsy findings

All

AKI

Non-AKI

No of patients (%)

37

13

24

Vacuole/hyaline droplet

34 (98.1)

12 (92.3)

22 (91.6)

Proteinaceous cast

17 (45.9)

8 (61.5)

9 (37.5)

Severe interstitial edemaa

6 (16.2)

3 (23.0)

3 (12.3)

Tubular necrosis/detachment

4 (10.8)

4 (30.7)

0 (0)*

Tubular simplificationb

19 (62.1)

11 (84.6)

9 (37.5)*

Interstitial lesionsc

6 (16.2)

4 (30.7)

2 (8.3)

Vascular lesionsd

13 (35.1)

6 (46.1)

7 (29.1)

Vimentin + tubules

25 (67.5)

11 (84.6)

14 (58.3)

Vimentin + tubular arease

11.3 ± 13.7

19.8 ± 18.3

6.8 ± 7.5*

  1. asevere interstitial edema with tubular collapse
  2. bloss of brush-border of the proximal tubule/dilated tubule with flattening of tubular epithelium
  3. cinterstitial inflammation/fibrosis
  4. darteriosclerosis or arteriolosclerosis
  5. emean percentage of vimentin-positive tubular areas
  6. *P < 0.05 vs. AKI group was indicated