Table 1 Variables definition in the CRONICAS Cohort Study and PREVENCION Study

Age

< 50, 50-69, ≥ 70 years.

Sex

Men or women.

Self-history of cardiovascular disease

Either heart attack, stroke or heart failure: yes or no.

Smoking^a

Last 12 months, have you smoked? Yes or no.

Hypertension

Defined as blood pressure ≥ 140/90 mmHg OR previous diagnosis of hypertension and currently under treatment [11].

Diabetes

Defined as fasting glucose ≥ 126 mg/dL OR diabetes diagnosed by a physician and currently under treatment.

Body Mass Index (BMI)

Categories: normal weight as [18.5-25[; overweight as [25-30[; and obesity as ≥ 30Kg/m².

Central obesity

Waist circumference ≥ 90 cm if male or ≥80 cm if female.

Parental history of early heart attack

Parents with heart attack before age 60: yes or no.

Anemia

Haemoglobin < 13 g/dL if male and < 12 g/dL if female [24].

Total Cholesterol

Borderline high or high if total cholesterol ≥200 mg/dL versus desirable if total cholesterol <200 md/dL [25].

HDL Cholesterol

High if ≥ 50 mg/dL if female or ≥ 40 mg/dL if male versus low otherwise [25].

LDL Cholesterol

Above optimal or high if LDL cholesterol ≥ 100 mg/dL versus optimal otherwise [25].

Triglycerides

High > 150 mg/dL or low ≤ 150 mg/dL [25].