Non-tunneled versus tunneled dialysis catheters for acute kidney injury requiring renal replacement therapy: a prospective cohort study

Table 1 Patient characteristics according to type of catheter used for AKI requiring renal replacement therapy

	NTDC only	TDC only	Both NTDC and TDC	p-value
Number of patients	77	35	42	–
Number of catheters	91	36	49 non-tunneled, 44 tunneled	–
Age, mean ± SD	61.1 ± 15.1	62.4 ± 15.6	62.6 ± 13.2	0.84
Female, %	40.3	48.6	42.9	0.71
Race, %				0.27
White	81.8	77.2	90.5
Black	5.2	14.3	4.8
Hispanic	2.6	5.7	4.8
Other	10.4	2.9	0
AKI severity of disease^a score, mean ± SD	26.4 ± 7.4	15.8 ± 5.1	21.5 ± 6.6	<0.001
Charlson score, median (IQR)	2 (1–3)	3 (2–5)	3 (1–5)	0.52
Hypertension, %	62.3	71.4	71.4	0.49
Diabetes mellitus, %	37.7	40.0	40.5	0.95
Chronic kidney disease, %	16.9	34.3	38.1	0.02
Congestive heart failure, %	19.5	14.3	35.7	0.05
Coronary artery disease, %	31.2	40.0	31.0	0.62
Hyperlipidemia, %	40.3	34.3	45.2	0.62
Malignancy, %	32.5	31.4	23.8	0.60
Cause of AKI				<0.001
ATN	63.6	34.3	59.5
Other^b	36.4	65.7	40.5
Primary team, %				<0.001
MICU	48.1	8.6	40.5
CCU	22.1	5.7	11.9
Medicine	3.9	40	9.5
Oncology	5.2	17.1	11.9
Other	20.8	28.6	26.2
Renal team, %				<0.001
Consult	7.8	77.1	31.0
ICU	90.1	22.9	69.1
Type of RRT, %^c				<0.001
IHD only	16.9	91.4	42.9
CVVH only	58.4	5.7	4.8
Both IHD and CVVH	24.7	2.9	52.4
Number of days on RRT, Median (IQR)^d	6 (3–11)	8 (4–13)	17 (10–28)	<0.001
In-hospital mortality, %	74.0	22.9	14.3	<0.001

AKI Acute kidney injury; ATN Acute tubular necrosis; CVVH Continuous veno-venous hemofiltration; CCU Coronary care unit; ICU Intensive care unit; IHD Intermittent hemodialysis; IQR Interquartile range; MICU, Medical intensive care unit; NTDC Non-tunneled dialysis catheter; RRT Renal replacement therapy; SD Standard deviation; TDC tunneled dialysis catheter
^aRisk equation by Demirjian et al. [13] calculated at time of initiation of RRT
^bOther common causes of AKI in descending order include: other (35.7%) pre-renal azotemia (3.3%), tumor lysis (3.3%), and acute interstitial nephritis (1.3%)
^cType of RRT, % - type of modality of RRT patient received while in the hospital
^dNumber of days on RRT – in-hospital number of days on RRT

ISSN: 1471-2369