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Table 2 Subgroup analyses of hypertension in patients with kidney stones

From: Nephrolithiasis and risk of hypertension: a meta-analysis of observational studies

Subgroup

No. of studies

OR (95% CI)

I2 (%)

P a

P b

Study design

 Cohort

4

1.33 (1.18, 1.49)

43.8

0.148

0.518

 Cross-sectional

5

1.47 (1.28, 1.70)

90.7

<0.001

Region

 USA

5

1.33 (1.26, 1.40)

37.8

0.154

0.106

 Non-USA

3

1.64 (1.26, 2.14)

86.3

0.001

 

Sample size

  < 35,000

5

1.59 (1.32, 1.92)

73.4

0.005

0.079

  ≥ 35,000

4

1.32 (1.25, 1.40)

54.3

0.087

Gender

 Men

4

1.31 (1.25, 1.37)

13.4

0.326

0.547

 Women

3

1.43 (1.21, 1.69)

78.2

0.010

Adjustment for confounding factors

  < 5

5

1.51 (1.30, 1.76)

91.2

<0.001

0.275

  ≥ 5

4

1.32 (1.14, 1.52)

0

0.497

  1. OR odds ratio, CI confidence interval
  2. a P value for heterogeneity among studies assessed with Cochran’s Q test
  3. b P value for interaction evaluated by meta-regression models