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Table 4 The characteristics in dialysis independent group and death or maintaining dialysis group according to the patient outcomes

From: The impact of intravenous methylprednisolone pulses on renal survival in anti-neutrophil cytoplasmic antibody associated vasculitis with severe renal injury patients: a retrospective study

Characteristics

Dialysis independent group (n = 25)

Death/ maintaining dialysis group (n = 81)

P value

Age (year)

59.5 ± 12.7

59.3 ± 15.1

0.950

Female (n, %)

20, 80.0

46, 56.8

0.058

White blood cells (109/L)

9.4 ± 4.6

8.0 ± 4.2

0.152

Hemoglobin (g/L)

74.0 ± 15.7

73.8 ± 12.7

0.969

Platelet (109/L)

225.2 ± 101.4

193.2 ± 86.1

0.122

Serum albumin (g/L)

31.5 ± 5.7

31.7 ± 5.0

0.907

Serum globulin (g/L)

30.5 ± 7.0

29.7 ± 5.3

0.554

Alanine transaminase (u/L)

14.8 ± 13.4

12.4 ± 7.3

0.392

Serum creatinine (μmol/L)

601.1 ± 150.3

718.4 ± 193.8

0.007

 ≥500 μmol/L (case, %)

18, 72.0

75, 92.6

0.012

eGFR (ml/min/1.73m2)

7.2 ± 1.9

6.5 ± 1.8

0.097

UPCR (g/24 h)

2.5 ± 0.7

3.4 ± 2.4

0.004

 ≥3.5g/24h (case, %)

3, 12.5

27, 35.5

0.041

ESR (mm/h)

83.0 ± 42.3

81.5 ± 37.1

0.875

CRP (mg/L)

48.0 ± 53.8

38.8 ± 45.2

0.401

MPO-ANCA positive (case, %)

22, 88.0

73, 92.4

0.446

PR3-ANCA positive (case, %)

4, 16.0

6, 7.7

0.251

Pulmonary involvement (case, %)

18, 72.0

61, 75.3

0.795

BVAS

14.6 ± 3.2

15.6 ± 2.8

0.174

Kidney length (cm)

10.6 ± 1.1

10.1 ± 1.4

0.113

Infection (case, %)

10, 40.0

31, 38.3

1.000

Intravenous methylprednisolone pulses (case, %)

21, 84.0

32, 39.5

<0.001

Kidney biopsy (case, %)

9, 36.0

23, 28.4

0.467

  1. eGFR Estimated glomerular filtration rate, UPCR Urine protein creatinine ratio, ESR Erythrocyte sedimentation rate, CRP C reactive protein, MPO Myeloperoxidase, PR3 Proteinase 3, BVAS Birmingham Vasculitis Activity Score