From: Establishing a clinical phenotype for cachexia in end stage kidney disease – study protocol
Unintentional oedema free weight loss ≥ 5% in 6 months or ≥ 10% 12 months (in the absence of documented weights, BMI < 20 kg/m2) and in the absence of starvation. |
Plus three of the following five criteria: |
1) Decreased muscle strength(lowest tertile); |
2) Fatigue (physical and/or mental weariness resulting from exertion not merely post-dialysis fatigue); |
3) Anorexia; |
4) Lean tissue depletion (in relation to aged /gender normative data) |
5) Abnormal biochemistry: increased inflammatory markers [CRP > 5 mg/L]; anaemia [haemoglobin < 120 g/L]; low serum albumin [< 32 g/L bromocresol green]. |