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Fig. 5 | BMC Nephrology

Fig. 5

From: MORG1+/− mice are protected from histological renal damage and inflammation in a murine model of endotoxemia

Fig. 5

a + b: Influence of LPS 24 h post endotoxemia on the blood concentrations of IL-6 and IFNγ in MORG1+/+ and MORG1+/− mice. a Plasma concentration of IL-6. LPS administration elevates significantly the IL-6 plasma levels in MORG1+/+ animals. Systemic IL-6 levels are reduced in LPS treated MORG1+/− mice in comparison to MORG1+/+ /LPS mice. N = 6 per group. *p < 0.05, **p < 0.01. b LPS treatment did not affect the IFNγ plasma levels in MORG1+/− mice compared with MORG1+/+ mice indicating that the suppression of IL-6 is not an unspecific effect. N = 6 per group

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BMC Nephrology

ISSN: 1471-2369

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