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Table 2 The association of gender with renal survival by Cox regression analysis before and after frequency matching of SUA levels and eGFR

From: Gender-related differences in clinicopathological characteristics and renal outcomes of Chinese patients with IgA nephropathy

Model

Hazard ratios (95% CI)

P-value

Before matching

 Univariate

1.39 (0.95, 2.03)

0.091

 Model 1: age, hypertension

1.12 (0.76, 1.65)

0.584

 Model 2: Model 1+ proportion of global glomerulosclerosis, S1, T1, T2

0.95 (0.62, 1.46)

0.824

 Model 3: Model 2 + Albumin, Proteinuria

0.97 (0.62, 1.50)

0.876

 Model 4: Model 3 + eGFR, SUA

0.59 (0.36, 0.95)

0.029

After matching

 Univariate

0.75 (0.48,1.18)

0.220

 Model 1: age, hypertension

0.62 (0.39,1.00)

0.052

 Model 2: Model 1 + proportion of global glomerulosclerosis, S1, T1, T2

0.73 (0.43,1.24)

0.248

 Model 3: Model 2+ Proteinuria

0.72 (0.42,1.23)

0.230

  1. CI confidence interval, eGFR estimated glomerular filtration rate, SUA serum uric acid, S segmental sclerosis, T tubular atrophy/interstitial fibrosis