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Table 4 Associated risk factors of renal survival in male patients

From: Gender-related differences in clinicopathological characteristics and renal outcomes of Chinese patients with IgA nephropathy

 

Univariate

Multivariate

Variables

HR (95% CI)

P-value

HR (95% CI)

P-value

Age (per 1-year increase)

1.00 (0.98, 1.03)

0.880

0.97 (0.94, 1.01)

0.139

Hypertension (vs. no)

2.43 (1.40, 4.23)

0.002

0.62 (0.32, 1.19)

0.150

Proteinuria (1 g/d increase)

1.28 (1.14, 1.43)

< 0.001

1.22 (1.02, 1.46)

0.032

eGFR (1 mL/min/1.73 m2 increase)

0.95 (0.94, 0.96)

< 0.001

0.95 (0.94, 0.97)

< 0.001

Proportion of global glomerulosclerosis (1% increase)

1.05 (1.04, 1.06)

< 0.001

1.02 (1.00, 1.04)

0.028

S1 (vs. S0)

3.60 (1.95, 6.61)

< 0.001

3.11 (1.49, 6.47)

0.002

T1 (vs. T0)

8.47 (4.25, 16.90)

< 0.001

0.83 (0.30, 2.28)

0.718

T2 (vs. T0)

41.65 (15.38, 112.79)

< 0.001

1.89 (0.50, 7.24)

0.351

  1. HR hazard ratio, CI confidence interval, eGFR estimated glomerular filtration rate, S segmental sclerosis, T tubular atrophy/interstitial fibrosis