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Table 5 Associated risk factors of renal survival in female patients

From: Gender-related differences in clinicopathological characteristics and renal outcomes of Chinese patients with IgA nephropathy

 

Univariate

Multivariate

Variable

HR (95% CI)

P-value

HR (95% CI)

P-value

Age (per 1-year increase)

0.99 (0.97, 1.02)

0.631

1.13 (0.92, 1.40)

0.242

Hypertension (vs. no)

4.85 (2.81, 8.36)

< 0.001

1.76 (0.85, 3.62)

0.126

Proteinuria (1 g/d increase)

1.76 (1.52, 2.04)

< 0.001

1.26 (1.03, 1.54)

0.023

eGFR (1 mL/min/1.73 m2 increase)

0.96 (0.95, 0.97)

< 0.001

0.98 (0.96, 0.99)

< 0.001

Proportion of global glomerulosclerosis (1% increase)

1.05 (1.04, 1.06)

< 0.001

1.10 (1.00, 1.21)

0.058

S1 (vs. S0)

4.93 (2.69, 9.02)

< 0.001

2.36 (1.42, 5.45)

0.012

T1 (vs. T0)

10.81 (5.75, 20.33)

< 0.001

1.75 (0.80, 3.81)

0.162

T2 (vs. T0)

31.43 (13.53, 73.02)

< 0.001

1.76 (0.58, 5.30)

0.318

  1. HR hazard ratio, CI confidence interval, eGFR estimated glomerular filtration rate, S segmental sclerosis, T tubular atrophy/interstitial fibrosis