Table 1 Baseline characteristics of patients according to BMI classification
| Â | BMI classification | Total | p-value | |||
|---|---|---|---|---|---|---|
Underweight | Normal | Overweight | Obesity | |||
Number | 99 | 403 | 220 | 422 | 1144 | Â |
BMI (kg/m2)a | 16.9 (15–17.8) | 21.1 (20.1–22.2) | 24.1 (13.5–24.5) | 27.5 (25.9–29.2) | 23.6 (20.9–26.3) | < 0.001 |
Age (yr) | 62.3 ± 17.2 | 65.0 ± 13.6 | 63.9 ± 14.0 | 61.3 ± 14.5 | 63.2 ± 14.4 | 0.002 |
Sex (Female, %) | 38 (38.4) | 162 (40.2) | 65 (29.5) | 174 (41.3) | 439 (38.4) | 0.03 |
DM (n, %) | 27 (27.6) | 140 (34.7) | 79 (35.9) | 153 (36.3) | 399 (34.9) | 0.42 |
HTN (n, %) | 40 (40.4) | 217 (53.8) | 110 (50.0) | 233 (55.3) | 600 (52.5) | 0.05 |
MI (n, %) | 10 (10.1) | 47 (11.7) | 17 (7.7) | 37 (8.8) | 111 (9.7) | 0.37 |
CHF (n, %) | 20 (20.2) | 71 (17.6) | 37 (16.8) | 57 (13.5) | 185 (16.2) | 0.26 |
CVA (n, %) | 7 (7.1) | 50 (12.4) | 25 (11.4) | 35 (8.3) | 117 (10.2) | 0.08 |
PVD (n, %) | 6 (6.1) | 15 (3.7) | 12 (5.5) | 13 (3.1) | 46 (4.0) | 0.35 |
COPD (n, %) | 11 (11.0) | 33 (8.2) | 13 (5.9) | 23 (5.5) | 80 (7.0) | 0.15 |
Cancer (n, %) | ||||||
 Solid tumor | 18 (18.4) | 96 (23.8) | 51 (23.3) | 93 (22.1) | 258 (22.6) |  |
 Metastasis | 5 (5.1) | 19 (4.7) | 18 (8.2) | 26 (6.2) | 68 (6.0) | 0.77 |
 Leukemia | 3 (3.1) | 19 (4.7) | 13 (5.9) | 16 (3.8) | 51 (4.5) |  |
 Lymphoma | 12 (12.2) | 37 (9.2) | 21 (9.6) | 38 (9.0) | 108 (9.5) |  |
CCI score | 3.1 ± 2.4 | 3.2 ± 2.2 | 3.1 ± 2.2 | 3.2 ± 2.3 | 3.2 ± 2.2 | 0.94 |
Sepsis (n, %) | 74 (74.7) | 294 (73.0) | 149 (67.7) | 280 (66.5) | 797 (69.7%) | 0.13 |
Postop AKI (n, %) | 3 (3.0) | 13 (3.2) | 9 (4.1) | 26 (6.2) | 51 (4.5) | 0.18 |
Cause of CRRT | ||||||
 Volume overload | 8 (8.1) | 62 (15.3) | 26 (11.8) | 64 (15.2) | 160 (13.9) |  |
 Metabolic acidosis | 26 (26.3) | 85 (21.1) | 43 (19.5) | 88 (20.8) | 242 (21.2) |  |
 Hyperkalemia | 2 (2.0) | 19 (4.7) | 12 (5.4) | 25 (5.9) | 58 (5.1) | 0.86 |
 Uremia | 13 (13.1) | 35 (8.7) | 21 (9.5) | 46 (10.9) | 115 (10.1) |  |
 Oliguria | 35 (35.4) | 112 (27.5) | 54 (24.5) | 93 (22.0) | 294 (25.7) |  |
 Others | 15 (15.2) | 90 (22.4) | 64 (29.1) | 106 (25.1) | 275 (24.0) |  |
CRRT dose (mL/kg) | 46.2 ± 16.4 | 44.6 ± 19.4 | 41.3 ± 15.1 | 40.0 ± 15.0 | 43.4 ± 16.9 | < 0.001 |
MAP (mmHg) | 76.6 ± 17.5 | 77.4 ± 14.2 | 77.3 ± 14.3 | 77.7 ± 14.5 | 77.5 ± 14.6 | 0.92 |
Creatinine (mg/dL) | 2.6 ± 1.5 | 2.5 ± 1.3 | 2.9 ± 1.9 | 2.9 ± 1.7 | 2.7 ± 1.6 | 0.001 |
eGFR (mL/min/1.73m2) | 33.2 ± 18.0 | 33.1 ± 22.3 | 32.7 ± 24.4 | 29.0 ± 18.8 | 31.5 ± 21.4 | 0.03 |
Albumin (g/dL) | 2.5 ± 0.5 | 2.6 ± 0.6 | 2.6 ± 0.6 | 2.6 ± 0.6 | 2.6 ± 0.6 | 0.47 |
Total cholesterol (mg/dL) | 111.9 ± 55.9 | 107.6 ± 48.5 | 98.1 ± 46.5 | 108.1 ± 68.9 | 106.2 ± 57.3 | 0.56 |
WBC (× 103/mm3) | 15.3 ± 25.9 | 13.8 ± 11.7 | 14.7 ± 12.8 | 13.7 ± 9.9 | 14.1 ± 13.2 | 0.64 |
Hemoglobin (g/dL) | 9.7 ± 2.4 | 9.7 ± 2.1 | 9.4 ± 2.4 | 9.6 ± 2.3 | 9.6 ± 2.3 | 0.56 |
CRP (mg/L)a | 37.1 (10.6–213.8) | 87.3 (17.7–171.7) | 72.9 (18.6–255.7) | 56.7 (14.2–151.8) | 67.5 (15.4–164.1) | 0.06 |
Vasopressor (n, %) | 68 (68.9) | 270 (67.0) | 165 (75.3) | 314 (74.4) | 817 (71.4) | 0.15 |
Ventilator (n, %) | 80 (81.0) | 345 (85.7) | 184 (83.7) | 352 (83.5) | 961 (84.0) | 0.74 |
SOFA | 11.3 ± 3.4 | 11.8 ± 3.7 | 12.0 ± 3.5 | 12.5 ± 3.5 | 12.1 ± 3.6 | 0.005 |
APACHE II | 26.4 ± 8.3 | 27.4 ± 8.0 | 27.5 ± 9.1 | 26.7 ± 8.4 | 27.1 ± 8.4 | 0.44 |