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Table 1 Characteristics of the matched cohort (IGT/IFG compared to normoglycaemia)

From: Risk of chronic kidney disease in young adults with impaired glucose tolerance/impaired fasting glucose: a retrospective cohort study using electronic primary care records

 

IGT/IFG

[N = 10,561 (26%)]

Normoglycaemia

[N = 29,531 (74%)]

P-Value

Age, mean [SD]

33.9

[5.3]

33.8

[5.4]

0.015††

Age, median [IQR]

35

[31, 38]

35

[31, 38]

 

Female, No. (%)

5659

(53.6)

15,795

(53.5)

0.863†

Years of follow-up, mean [SD]

2.3

[2.1]

2.3

[2.0]

0.684†††

Years of follow-up, median [IQR]

1.68

[0.81, 3.16]

1.67

[0.79, 3.14]

 

Ethnicity, No. (%)

 White

3644

(34.5)

11,305

(38.3)

< 0.001†

 Black

392

(3.7)

784

(2.7)

 

 Asian

1483

(14.0)

1902

(6.4)

 

 Chinese

32

(0.3)

102

(0.4)

 

 Mixed

63

(0.6)

219

(0.7)

 

 Others

130

(1.2)

333

(1.1)

 

 Unknown

4817

(45.6)

14,886

(50.5)

 

Deprivation quintile, No. (%)

 (least deprived) 1

1509

(14.3)

5229

(17.7)

< 0.001†

 2

1575

(14.9)

4985

(16.9)

 

 3

2177

(20.6)

6149

(20.8)

 

 4

2463

(23.3)

6319

(21.4)

 

 (most deprived) 5

2232

(21.1)

5020

(17.0)

 

 Unknown

605

(5.7)

1829

(6.2)

 

CVD at index date, No. (%)

190

(1.8)

274

(0.9)

< 0.001†

HF at index date, No. (%)

29

(0.30)

21

(0.07)

< 0.001†

AF at index date, No. (%)

17

(0.16)

21

(0.07)

0.010†

Hypertension at index date, No. (%)

1112

(10.5)

548

(1.9)

< 0.001†

Prescription of NSAID, No. (%)

200

(1.9)

120

(0.4)

< 0.001†

BMI (kg/m2), No. (%)

  < 20

332

(3.1)

2191

(7.4)

< 0.001††

 20–24.9

1542

(14.6)

9452

(32.0)

 

 25–29.9

2420

(22.9)

7028

(23.8)

 

 30–34.9

2104

(19.9)

2868

(9.7)

 

 35–39.9

1585

(15.0)

1071

(3.6)

 

  ≥ 40

1575

(15.0)

644

(2.2)

 

 Unknown

1003

(9.5)

6277

(21.2)

 

BMI (kg/m2), mean [SD]

26.0

[5.7]

32.1

[8.2]

< 0.001††

BMI (kg/m2), median [IQR]

31

[26, 37.1]

24.9

[22.1, 28.7]

 

T2DM during follow-up, No. (%)

1262

(11.9)

124

(0.4)

< 0.001†

CKD during follow-up, No. (%)

182

(1.7)

126

(0.4)

< 0.001†

Country, No. (%)

 England

8516

(80.6)

23,661

(80.0)

0.688†

 Northern Ireland

270

(2.6)

791

(2.7)

 

 Scotland

804

(7.6)

2321

(7.9)

 

 Wales

971

(9.2)

2758

(9.3)

 
  1. Values are numbers (percentages) unless otherwise specified. P-values are from X2 test (†) for proportions or t-test (††) for continuous variables (age, BMI) and Mann-Whitney U test (†††) for follow-up
  2. Abbreviations: CVD cardiovascular disease, HF heart failure, AF atrial fibrillation, NSAID non-steroidal anti-inflammatory drug, BMI body mass index, IQR interquartile range
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