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Table 2 Clinical outcomes of study patients

From: Increased urinary excretion of kynurenic acid is associated with non-recovery from acute kidney injury in critically ill patients

 

Early Recovery

Late/Non-Recovery

p-value

Number

67

25

 

Maximum creatinine level, mg/dl (mean ± SD)

2.0 ± 0.9

3.6 ± 2.0

< 0.0001

Minimal eGFR, ml/min (mean ± SD)

45 ± 25

21 ± 9

< 0.0001

RIFLE class, R/I/F

42/18/7

0/6/19

< 0.0001

Duration of AKI, days (mean ± SD)

3.0 ± 1.8

21.5 ± 19.8

< 0.0001

Patients on RRT, n (%)

2 (3)

15 (63)

< 0.0001

Patients with RBC transfusions, n (%)

30 (45)

19 (76)

0.01

Red blood cell transfusions, n (mean ± SD)

1.4 ± 2.3

3.7 ± 4.1

< 0.001

Length of hospital stay, days (mean ± SD)

34 ± 33

50 ± 31

< 0.005

Length of ICU stay, days (mean ± SD)

18 ± 20

31 ± 26

< 0.01

28-day mortality, n (%)

13 (20)

11 (46)

< 0.05

90-day mortality, n (%)

25 (34)

15 (63)

NS

  1. AKI acute kidney injury, eGFR estimated glomerular filtration rate, ICU intensive care unit, RBC red blood cellm, R Risk, I Injury, F Failure, RRT renal replacement therapy