| DAY 1 | DAY 2 | DAY 3 | |||||||
---|---|---|---|---|---|---|---|---|---|---|
ER | LNR | p | ER | LNR | p | ER | LNR | p | ||
Trp/cr | umol/mmol | 5.51 ± 4.95 | 6.10 ± 6.75 | NS | 9.50 ± 14.91 | 7.28 ± 7.84 | NS | 12.08 ± 10.49 | 6.0 ± 5.6 | < 0.005 |
Kyn/cr | umol/mmol | 2.90 ± 4.87 | 2.94 ± 7.65 | NS | 3.88 ± 5.69 | 4.30 ± 8.80 | NS | 5.60 ± 8.17 | 2.2 ± 4.8 | < 0.0001 |
KynA/cr | umol/mmol | 3.19 ± 3.44 | 7.59 ± 6.81 | < 0.005 | 1.87 ± 1.10 | 9.17 ± 9.67 | < 0.0001 | 2.00 ± 1.28 | 6.51 ± 9.49 | < 0.001 |
3 OH AA/cr | umol/mmol | 1.36 ± 2.86 | 1.04 ± 1.82 | NS | 1.14 ± 1.62 | 0.72 ± 1.04 | NS | 2.02 ± 3.11 | 0.75 ± 0.99 | < 0.05 |
Serotonine/cr | umol/mmol | 0.045 ± 0.075 | 0.053 ± 0.11 | NS | 0.038 ± 0.026 | 0.036 ± 0.041 | NS | 0.045 ± 0.035 | 0.027 ± 0.037 | < 0.005 |
Phenylalanine/cr | umol/mmol | 5.50 ± 5.02 | 9.41 ± 12.84 | NS | 7.56 ± 11.80 | 9.77 ± 12.03 | NS | 8.49 ± 7.55 | 6.73 ± 6.81 | NS |
OH-Trp/cr | umol/mmol | 0.12 ± 0.18 | 0.23 ± 0.72 | NS | 0.11 ± 0.077 | 0.13 ± 0.106 | NS | 0.11 ± 0.068 | 0.11 ± 0.078 | NS |
KynA/Trp |  | 1.37 ± 2.86 | 2.30 ± 2.73 | < 0.01 | 0.47 ± 0.66 | 1.8 ± 1.8 | < 0.0001 | 0.26 ± 0.20 | 1.33 ± 1.25 | < 0.0001 |
Kyn/Trp |  | 0.66 ± 1.24 | 0.34 ± 0.33 | NS | 0.64 ± 1.08 | 0.58 ± 0.93 | NS | 0.73 ± 1.58 | 0.30 ± 0.41 | < 0.05 |