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Fig. 1 | BMC Nephrology

Fig. 1

From: Immune checkpoint inhibitor (nivolumab)-associated kidney injury and the importance of recognizing concomitant medications known to cause acute tubulointerstitial nephritis: a case report

Fig. 1

Light microscopy. a Hematoxylin and eosin staining. The glomeruli are mostly intact; however, marked infiltration of inflammatory cells (predominantly lymphocytes) in the interstitial space is observed (arrow). Eosinophils are not conspicuous and granuloma formation is not noted (× 200). b Periodic acid-Schiff staining. Lymphocyte invasion into the tubules and degeneration of tubular epithelial cells (tubulitis) are noted (arrows) (× 400). c Immunohistochemical study of CD4. The infiltrated cells are CD4 positive (arrow) (× 400)

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BMC Nephrology

ISSN: 1471-2369

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