The association between soluble klotho and cardiovascular parameters in chronic kidney disease: results from the KNOW-CKD study

Table 2 Multivariable linear regression analysis presenting associations between klotho and left ventricular mass index

Variable	Model A		Model B		Model C
	β (95% CI)	P- value	β (95% CI)	P- value	β (95% CI)	P- value
Klotho (pg/mL)	− 0.09 (− 0.006, − 0.002)	< 0.001	−0.079 (− 0.005, − 0.002)	< 0.001	−0.04 (− 0.004, − 0.00007)	0.041

Model A: Adjusted for klotho, age and gender
Model B: Adjusted for klotho, age, gender, DM, HTN, BMI, and SBP
Model C: Adjusted for klotho, age, gender, DM, HTN, BMI, SBP, eGFR, hemoblogin, phosphorus, corrected Ca, and FGF23
β, Standardized coefficient; CI, confidence interval; DM, diabetes mellitus; HTN, hypertension; BMI, body mass index; SBP, systolic blood pressure; eGFR, estimated glomerular filtration rate by CKD-EPI creatinine equation; Ca, calcium; FGF23, fibroblast growth factor 23

ISSN: 1471-2369