Table 1 Clinical and biological characteristics of the patients at the initiation of hemodialysis
Variables | All group n = 250 | Initial urine volume (ml/day) | p | |
|---|---|---|---|---|
≤ 500 n = 123 | > 500 n = 127 | |||
Age, years | 52.5 ± 12.4 | 52.1 ± 13.3 | 52.8 ± 11.5 | 0.683 |
Sex, female, n (%) | 78 (31.2) | 44 (35.8) | 34 (26.8) | 0.125 |
Diabetes mellitus, n (%) | 98 (39.2) | 48 (39.0) | 50 (39.4) | 0.955 |
SBP, mm Hg | 153.8 ± 27.2 | 153.4 ± 27.3 | 154.1 ± 27.3 | 0.821 |
DBP, mm Hg | 84.7 ± 18.3 | 84.0 ± 17.5 | 85.2 ± 19.1 | 0.604 |
PP, mm Hg | 69.1 ± 20.8 | 69.4 ± 19.9 | 68.9 ± 21.8 | 0.861 |
Hypertension, n (%) | 217 (86.8) | 104 (84.6) | 113 (89.0) | 0.302 |
Diuretics, n (%) | 133 (53.2) | 57 (46.3) | 76 (59.8) | 0.032 |
ACE inhibitors, n (%) | 138 (55.2) | 55 (44.7) | 83 (65.4) | 0.001 |
ARB, n (%) | 29 (11.6) | 12 (9.8) | 17 (13.4) | 0.370 |
Hypovolemia, n (%) | 40 (16.0) | 12 (9.8) | 28 (22.1) | 0.008 |
Hypervolemia, n (%) | 95 (38.0) | 68 (55.3) | 27 (21.3) | < 0.001 |
eGFR-MDRD, ml/min/1.73 m2 | 5.0 (3.0–8.0) (n = 240) | 4.0 (3.0–8.0) (n = 115) | 6.0 (4.0–8.0) (n = 125) | 0.023 |
Serum creatinine, mg/dl | 12.0 (8.2–17.8) (n = 240) | 13.0 (8.4–20.0) (n = 115) | 11.0 (8.0–16.0) (n = 125) | 0.036 |
Serum urea, mg/dl | 197 (147–288) (n = 239) | 223 (168–331) (n = 115) | 187 (139–261) (n = 124) | 0.004 |
Serum potassium, mmol/l | 5.2 ± 1.4 (n = 239) | 5.4 ± 1.4 (n = 115) | 4.9 ± 1.3 (n = 124) | 0.007 |
Hemoglobin level, g/dl | 8.5 ± 2.2 (n = 249) | 8.2 ± 2.2 (n = 122) | 8.8 ± 2.2 (n = 127) | 0.042 |
Proteinuria, g/24 h | (n = 77) | (n = 26) | (n = 51) | 0.343 |
< 1, n (%) | 22 (28.6) | 6 (23.1) | 16 (31.4) | |
1–3, n (%) | 41 (53.2) | 13 (50.0) | 28 (54.9) | |
> 3, n (%) | 14 (18.2) | 7 (26.9) | 7 (13.7) | |
Serum albumin, g/l | 36.8 ± 7.3 (n = 234) | 35.6 ± 7.4 (n = 116) | 38.1 ± 7.0 (n = 118) | 0.007 |
Interstitial initial nephropathy, n (%) | 23 (9.2) | 9 (7.3) | 14 (11.0) | 0.311 |
Left ventricular hypertrophy, n (%) | 101 (42.8) (n = 236) | 55 (47.8) (n = 115) | 46 (38.0) (n = 121) | 0.200 |
Congestive heart failure, n (%) | 86 (34.4) | 47 (38.2) | 39 (30.7) | 0.212 |
≥ 3 times hemodialysis weekly, n (%) | 116 (46.4) | 60 (48.8) | 56 (44.1) | 0.458 |