Table 7 Treatment effect of dialysate to serum sodium alignment on volume-related and hemodynamic parameters in those patients part to this quality initiative (intention-to-treat cohort; N = 163) and the propensity score matched control cohort (N = 163)
Parameter | Study Regimen | Baseline | Follow-up | Difference (95% CI) | Treatment effect (95% CI) |
|---|---|---|---|---|---|
Pre HD SBP [mmHg] | aligned | 145.17+/−20.05 | 143.95+/−20.57 | −1.22 (−5.65 to 3.2) | 1.19 (−1.07 to 3.44) |
unaligned | 145.12+/−19.33 | 142.7+/−19.7 | −2.41 (−6.66 to 1.84) | ||
Post HD SBP [mmHg] | aligned | 135.1+/−17.72 | 134.36+/−17.68 | −0.74 (−4.6 to 3.12) | 1.21 (−0.86 to 3.28) |
unaligned | 137.08+/−18.12 | 135.1+/−18.3 | −1.95 (−5.92 to 2.02) | ||
Pre HD DBP [mmHg] | aligned | 74.12+/−12.25 | 73.59+/−12.16 | −0.53 (−3.19 to 2.13) | 0.3 (−0.91 to 1.51) |
unaligned | 75.62+/−11.47 | 74.8+/−11.1 | −0.83 (−3.3 to 1.63) | ||
Post HD DBP [mmHg] | aligned | 69+/−10.39 | 68.83+/−10.49 | −0.17 (−2.45 to 2.1) | 0.43 (−0.67 to 1.53) |
unaligned | 71.39+/−10.21 | 70.8+/−10.1 | −0.6 (−2.82 to 1.61) | ||
Pre HD PP [mmHg] | aligned | 71.06+/−14.92 | 70.36+/−15.52 | −0.69 (−4.01 to 2.62) | 0.89 (−0.59 to 2.36) |
unaligned | 69.5+/−14.11 | 67.9+/−14.9 | −1.58 (−4.74 to 1.58) | ||
Post HD PP [mmHg] | aligned | 66.1+/−12.89 | 65.53+/−13.09 | −0.57 (−3.4 to 2.27) | 0.78 (−0.59 to 2.15) |
unaligned | 65.69+/−13.27 | 64.3+/−13.6 | −1.35 (−4.27 to 1.58) | ||
Pre HD MAP [mmHg] | aligned | 97.8+/−13.58 | 97.04+/−13.64 | −0.76 (−3.73 to 2.21) | 0.6 (−0.88 to 2.08) |
unaligned | 98.79+/−12.96 | 97.4+/−12.7 | −1.36 (−4.16 to 1.44) | ||
Post HD MAP [mmHg] | aligned | 91.03+/−11.82 | 90.67+/−11.81 | −0.36 (−2.94 to 2.21) | 0.69 (−0.66 to 2.04) |
unaligned | 93.29+/−11.83 | 92.2+/−11.8 | −1.05 (−3.63 to 1.52) | ||
Intra HD SBP change [mmHg] | aligned | −10.07+/−13.7 | −9.59+/−13.34 | 0.48 (−2.46 to 3.43) | 0.02 (−2.12 to 2.16) |
unaligned | −8.04+/−13.94 | −7.6+/−13.5 | 0.46 (−2.53 to 3.45) | ||
Intra HD DBP change [mmHg] | aligned | −5.12+/−6.81 | −4.76+/−6.47 | 0.36 (−1.09 to 1.8) | 0.13 (−0.9 to 1.15) |
unaligned | −4.24+/−6.59 | −4+/−6.5 | 0.23 (−1.2 to 1.66) |