Table 2 Case and control subject characteristics
From: Serum BTP concentrations are not affected by hepatic dysfunction
Characteristic | Case (n = 99) | Controls (n = 99) | P value |
|---|---|---|---|
Male, N (%) | 70 (71) | 70 (71) | 0.88 |
Age, (SD) years | 59.4 (7.9) | 60.4 (8.6) | 0.40 |
Diabetes, N(%) | 31 (31) | 31 (31) | 0.88 |
Cirrhosis etiology | Not applicable | ||
Hepatitis C | 38 (38) | ||
Ethanol | 21 (21) | ||
NASH | 21 (21) | ||
Hepatitis B | 2 (2) | ||
Autoimmune | 2 (2) | ||
Other (PBC, NYD) | 6 (6) | ||
Cr, mean (SD), 95% CI, mg/dL | 0.85 (0.25) | 2.59 (0.28) | < 0.001 |
0.77–0.93 | 2.50–2.67 | ||
BTP, mean (SD), 95% CI, mg/L | 0.93 (0.41) | 1.92 (1.4) | < 0.001 |
0.85–1.01 | 1.84–2.00 | ||
CysC, mean (SD), 95% CI, mg/L | 1.17 (0.44) | 2.24 (1.16) | < 0.001 |
1.09–1.25 | 2.16–2.32 | ||
Bilirubin | Not measured | ||
mean (SD), mg/dL | 1.6 (1.4) | ||
< 2 mg/dL, N(%) | 77 (78) | ||
2–3 mg/dL, N(%) | 9 (9) | ||
> 3 mg/dL, N(%) | 13 (13) | ||
Albumin | Not measured | ||
mean (SD), g/dL | 3.4 (0.6) | ||
> 3.5 g/dL, N(%) | 47 (48) | ||
2.8–3.5 g/dL, N(%) | 42 (42) | ||
< 2.8 g/dL, N(%) | 10 (10) | ||
INR | Not measured | ||
mean (SD) | 1.3 (0.3) | ||
< 1.7, N(%) | 90 (91) | ||
1.7–2.3, N(%) | 8 (8) | ||
> 2.3, N(%) | 1 (1) | ||
Ascites N(%) | |||
None, | 64 (65) | 99 | |
Mild, | 33 (33) | 0 | |
Moderate-Severe | 2 (2) | 0 | |
Encephalopathy, N(%) | |||
None | 80 (81) | 99 | |
Grade I-II | 19 (19) | 0 | |
Grade III-IV | 0 (0) | 0 | |
CHILD PUGH category N (%) | |||
A | 60 (61) | Not applicable | |
B | 27 (27) | ||
C | 12 (12) | ||
MELD score N (%) | |||
≤ 9.4 | 50 (47.6) | Not applicable | |
9.5–19 | 51 (48.6) | ||
20–29 | 4 (3.8) | ||