Biomarkers | Models | MA |
|---|
OR value (95% CI) | P value |
|---|
Homocysteine (μmol/L) | 1st stepa | 1.066 (1.041–1.092) | < 0.001 |
2nd stepb | 1.059 (1.031–1.087) | < 0.001 |
3rd stepc | 1.059 (1.032–1.087) | < 0.001 |
HsCRP (mg/dl) | 1st stepa | 0.742 (0.426–1.293) | 0.293 |
2nd stepb | 0.544 (0.256–1.160) | 0.115 |
3rd stepc | 0.490 (0.218–1.098) | 0.083 |
NT-proBNP (pg/mL) | 1st stepa | 1.002 (1.001–1.003) | 0.006 |
2nd stepb | 1.002 (1.000–1.003) | 0.020 |
3rd stepc | 1.001 (1.000–1.003) | 0.043 |
UA (μmol/L) | 1st stepa | 1.002 (0.999–1.005) | 0.111 |
2nd stepb | 1.001 (0.998–1.005) | 0.415 |
3rd stepc | 1.001 (0.998–1.005) | 0.478 |
- Note: aFirst step: single biomarker in the logistic regression model adjusted by age and gender; bSecond step: single biomarker in the logistic regression model adjusted by age, gender, body mass index, cigarette smoking, systolic blood pressure, triglyceride, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, fasting blood glucose and glomerular filtration rate; cThird step: all biomarkers simultaneously in the logistic regression model adjusted by age, gender, body mass index, cigarette smoking, systolic blood pressure, triglyceride, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, fasting blood glucose and glomerular filtration rate
- Abbreviation: MA microalbuminuria, OR odd ratio, CI confidence interval, hsCRP high-sensitivity C-reactive protein, NT-proBNP N-terminal prohormone of brain natriuretic peptide, UA uric acid
