Table 3 Characteristics of body mass index subgroups in the acute kidney injury [actual body weight] and [ideal body weight] groups
Group | AKI [ABW] | AKI [IBW] | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Subgroup | Under weight | Normal | Over weight | Obese | P-value | Under weight | Normal | Over weight | Obese | P-value |
Patients (n) | 12 | 83 | 40 | 18 | 19 | 80 | 28 | 13 | ||
Age, years | 60 (53–69) | 69 (62–78) | 73 (64–79) | 60 (44–72) | 0.006 | 66 (53–77) | 69 (61–78) | 75 (66–80) | 59 (46–70) | 0.015 |
Male sex, No. | 7 (58.4%) | 51 (61.5%) | 20 (50.0%) | 11 (61.1%) | 0.676 | 12 (63.1%) | 52 (65.0%) | 16 (57.1%) | 9 (69.2%) | 0.861 |
Body weight, kg | 42 (40–48) | 55 (50–60) | 67 (58–73) | 90 (76–95) | < 0.0001 | 43 (40–49) | 58 (51–61) | 67 (58–73) | 92 (80–97) | < 0.0001 |
Height, cm | 159 (151–175) | 160 (153–166) | 156 (147–166) | 164 (154–170) | 0.283 | 160 (150–174) | 160 (155–167) | 156 (147–166) | 165 (160–171) | 0.103 |
BMI, kg/m2 | 16.9 (16.0–17.8) | 22.1 (20.3–23.6) | 26.6 (25.8–27.9) | 32.4 (31.3–38.2) | < 0.0001 | 17.1 (16.0–17.8) | 22.1 (20.8–23.6) | 26.5 (25.5–27.8) | 32.1 (30.8–34.2) | < 0.0001 |
Premorbid creatinine, mg/dL | 0.74 (0.56–0.86) | 0.84 (0.70–1.25) | 0.77 (0.61–1.06) | 0.89 (0.63–1.23) | 0.332 | 0.75 (0.56–0.91) | 0.85 (0.70–1.29) | 0.78 (0.67–1.06) | 0.96 (0.60–1.31) | 0.433 |
Highest creatinine level within 48 h, mg/dL | 1.83 (1.08–2.61) | 2.27 (1.16–4.18) | 2.13 (1.11–3.07) | 2.53 (1.22–4.09) | 0.366 | 1.51 (0.84–2.59) | 2.31 (1.36–4.20) | 2.56 (1.53–3.60) | 2.92 (2.10–5.50) | 0.018 |
Highest cystatin C level within 48 h, ng/dL | 2.78 (2.32–3.64) | 2.31 (1.49–3.36) | 1.74 (1.01–2.58) | 1.97 (1.29–4.78) | 0.036 | 2.46 (1.00–3.08) | 2.27 (1.46–3.36) | 1.92 (1.58–3.05) | 2.85 (1.97–4.40) | 0.596 |
SAPS II | 65 (46–83) | 63 (52–75) | 64 (55–76) | 58 (45–78) | 0.886 | 55 (44–77) | 64 (51–75) | 67 (60–81) | 62 (49–81) | 0.105 |
SOFA score | 10 (7–14) | 9 (6–11) | 8 (6–11) | 11 (8–13) | 0.406 | 7 (4–12) | 9 (7–11) | 11 (7–13) | 12 (9–13) | 0.082 |
ISTH DIC, No. | 45.5% | 41.5% | 28.2% | 27.8% | 0.393 | 33.3% | 45.6% | 29.6% | 30.8% | 0.388 |
Septic shock, No. | 66.7% | 56.6% | 50.0% | 66.7% | 0.584 | 42.1% | 58.8% | 60.7% | 69.2% | 0.433 |
Urinary diagnosis of AKI, No. | 0.446 | 0.439 | ||||||||
Stage 1 | 3 (25.0%) | 26 (31.3%) | 17 (42.5%) | 5 (27.8%) | 8 (42.1%) | 24 (30.0%) | 9 (32.1%) | 4 (30.8%) | ||
Stage 2 | 4 (33.3%) | 17 (20.5%) | 12 (30.0%) | 5 (27.8%) | 6 (31.6%) | 17 (21.3%) | 8 (28.6%) | 1 (7.7%) | ||
Stage 3 | 5 (41.7%) | 40 (48.2%) | 11 (27.5%) | 8 (44.4%) | 5 (26.3%) | 39 (48.8%) | 11 (39.3%) | 8 (61.5%) | ||
MV, No. | 83.3% | 86.8% | 100.0% | 94.4% | 0.078 | 79.0% | 86.3% | 100.0% | 92.3% | 0.114 |
Duration of MV, day | 8 (6–13) | 8 (6–16) | 11 (6–14) | 8 (5–16) | 0.803 | 10 (7–12) | 9 (6–16) | 11 (6–20) | 7 (4–15) | 0.535 |
Days of ICU stay | 11 (6–12) | 9 (7–16) | 13 (8–17) | 10 (5–18) | 0.429 | 11 (5–13) | 9 (6–16) | 13 (7–22) | 8 (4–16) | 0.272 |
90-day mortality | 76.7% | 39.5% | 26.0% | 35.7% | 0.033 | 49.2% | 40.8% | 37.8% | 48.7% | 0.736 |