Cardiac structure | ||||||
LAD (mm) | LVEDD (mm) | LVESD (mm) | LVEDV (mm3) | LVESV (mm3) | IVS (mm) | |
Icodextrin | ||||||
Baseline (n = 21) | 34.97 ± 7.51 | 50.80 ± 7.66 | 35.00 ± 6.35 | 124.71 ± 42.49 | 53.48 ± 21.83 | 12.65 ± 2.29 |
After 12 months (n = 21) | 36.90 ± 61.16 | 50.48 ± 7.93 | 34.90 ± 6.86 | 127.76 ± 40.22 | 50.24 ± 19.79 | 12.76 ± 2.10 |
After 24 months (n = 20) | 35.90 ± 10.99 | 50.85 ± 14.59 | 32.05 ± 10.46 | 121.35 ± 59.03 | 46.20 ± 31.98 | 11.45 ± 4.48 |
P - value | 0.001 | 0.195 | 0.063 | 0.003 | 0.004 | 0.004 |
Glucose | ||||||
Baseline (n = 22) | 32.25 ± 5.88 | 46.88 ± 6.36 | 30.49 ± 6.14 | 103.95 ± 34.34 | 39.00 ± 22.22 | 11.53 ± 1.79 |
After 12 months (n = 21) | 33.90 ± 5.08 | 47.24 ± 7.50 | 31.52 ± 6.61 | 106.43 ± 40.43 | 42.52 ± 23.15 | 11.33 ± 1.91 |
After 24 months (n = 18) | 34.83 ± 5.45 | 49.22 ± 8.43 | 31.67 ± 7.47 | 118.39 ± 47.99 | 43.67 ± 27.06 | 11.33 ± 1.78 |
P - value | 0.005 | 0.001 | 0.001 | < 0.001 | 0.001 | 0.005 |
LV systolic function | LV diastolic function | |||||
MPI | LVEF (%) | DT (ms) | Peak EDV (cm/s) | Septal EMV (ms) | E/e′ | |
Icodextrin | ||||||
Baseline (n = 21) | 0.37 ± 0.19 | 57.81 ± 10.03 | 169.81 ± 73.50 | 71.89 ± 34.66 | 5.43 ± 3.00 | 11.70 ± 6.36 |
After 12 months (n = 21) | 0.43 ± 0.20 | 60.43 ± 7.29 | 214.24 ± 72.01 | 73.89 ± 27.94 | 6.05 ± 2.42 | 12.83 ± 6.60 |
After 24 months (n = 20) | 0.32 ± 0.21 | 56.55 ± 21.88 | 193.35 ± 75.03 | 65.80 ± 33.68 | 5.51 ± 2.28 | 11.51 ± 9.60 |
P - value | 0.195 | 0.068 | 0.081 | 0.150 | 0.035 | 0.104 |
Glucose | ||||||
Baseline (n = 22) | 0.49 ± 0.57 | 63.40 ± 9.51 | 213.60 ± 85.21 | 70.67 ± 28.75 | 5.94 ± 1.58 | 12.38 ± 5.24 |
After 12 months (n = 21) | 0.35 ± 0.18 | 60.67 ± 8.50 | 199.62 ± 79.76 | 66.52 ± 23.69 | 5.97 ± 3.11 | 10.46 ± 5.05 |
After 24 months (n = 18) | 0.30 ± 0.19 | 64.50 ± 8.58 | 201.94 ± 62.55 | 68.25 ± 20.31 | 7.57 ± 3.42 | 9.08 ± 4.35 |
P - value | 0.174 | 0.015 | 0.051 | 0.036 | 0.013 | 0.052 |