Table 5 Multivariate model analysis for the primary end points at 24 months
End Point | Parameter | Estimate | SE | t | P | n | R 2 | Adjusted R2 |
|---|---|---|---|---|---|---|---|---|
MPI | Intercept | 0.03 | 0.08 | 0.41 | 0.682 | 38 | 0.01 | −0.05 |
Baseline MPI | −0.02 | 0.07 | −0.34 | 0.733 | ||||
Icodextrin (vs. glucose) | 0.31 | 0.05 | 5.60 | 0.000 | ||||
LVEF | Intercept | 0.33 | 0.30 | 1.10 | 0.280 | 38 | 0.09 | 0.03 |
Baseline LVEF | 6.60 | 5.63 | 1.17 | 0.249 | ||||
Icodextrin (vs. glucose) | 37.01 | 18.20 | 2.03 | 0.050 | ||||
DT | Intercept | 0.23 | 0.20 | 1.16 | 0.253 | 38 | 0.04 | −0.01 |
Baseline DT | 3.92 | 22.80 | 0.17 | 0.864 | ||||
Icodextrin (vs. glucose) | 152.00 | 38.78 | 3.92 | 0.000 | ||||
E/e′ | Intercept | 0.32 | 0.27 | 1.18 | 0.248 | 35 | 0.06 | 0.00 |
Baseline E/e′ | −1.74 | 2.65 | −0.66 | 0.517 | ||||
Icodextrin (vs. glucose) | 7.33 | 3.75 | 1.95 | 0.060 |