Table 1 Clinical evolution of CAPS in the described patient
Organ manifestation | Clinical signs | Laboratory abnormalities typical for CAPS | Laboratory tests which were normal |
|---|---|---|---|
Kidneys | |||
renal failure | Peripheral edema | Thrombocytopenia | Fibrinogen |
renal vein thrombosis | Fluid in both pleural cavities | Elongate APTT | ANA |
hematuria | Elevated D-dimer | Anti-dsDNA | |
proteinuria | Reduced complement components C3 and C4 | ADAMTS 13 and its inhibitor | |
Brain | |||
stroke | Positive lupus anticoagulant | ||
Skin | |||
livedo reticularis | livedo reticularis | Antiβ2glicoprotein-I antibodies | |
Peripheral vessel | |||
peripheral venous thrombosis | Edema of the legs | Thrombotic microangiopathy in renal biopsy | |
Eye | |||
central retinal artery thrombosis | Blurred vision | ||