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Fig. 2 | BMC Nephrology

Fig. 2

From: C3 glomerulonephritis and thrombotic microangiopathy of renal allograft after pulmonary infection in a male with concomitant two complement factor I gene variations: a case report

Fig. 2

a Pedigree and chromatograms of CFI gene sequence alterations.Our patient’s father and mother are heterozygous for the c.848A > G and c.1139G > T variants respectively while his sister has neither of the two variants. b Schematic representation of main protein domains of CFI protein. FIMAC is the factor I membrane attack complex. SR is the scavenger receptor cysteine-rich domain. Ldla represents low density lipoprotein receptor class A domain. Ldlra is low-density lipoprotein receptor domain class A

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BMC Nephrology

ISSN: 1471-2369

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