Table 1 Laboratory workups and results of diagnostic procedures

Tested parameters (Patient)

Result (range)

 Urine protein (g/24 h)

4.16 (< 0.4)

 Hemoglobin (g/L)

101 (130–175)

 Platelet count

74 × 10^9 (100–300 × 10⁹)

 Serum C3 (g/L)

0.76 (0.8–1.8)

 Serum C4 (g/L)

0.1 (0.1–0.4)

 Serum CFH (ug/ml)

360.7 (200–1000)

 Serum CFH antibody

Negative

 Serum C3 nephrotic factor

Negative

 DSA

Negative

 ADAMTS13 activity (ng/ml)

827.1 (424–1098)

 ADAMTS13 antibody (Au/ml)

7.68 (< 27)

 Vascular cell adhesion molecule (ng/ml)

1192.73 (300–1000)

 Anti-cardiolipin antibody

Negative

 Cold agglutinin (mg/L)

20 (< 192)

 HBV/HCV/HIV

Negative

 Serum immunofixation electrophoresis

Negative

 Bone marrow aspirate

Negative

Serum CFI quantity (ug/ml)

Normal range: 16–75

 The patient

53.84

 Patient’s father

20.2

 Patient’s mother

36.6

 Patient’s sister

56.6