Fig. 6From: Angiotensin II-induced podocyte apoptosis is mediated by endoplasmic reticulum stress/PKC-δ/p38 MAPK pathway activation and trough increased Na+/H+ exchanger isoform 1 activitypHi recovery after acid loading. a Representative experiment of podocytes exposed to Na+-control solution, Na+-free solution with N-methyl-D-glucamine-NMDG (138 mM), followed by replacement of Na+-control solution (Na+ 138 mM). b pHi recovery rate using NMDG and Na+ solutions (138 mM). c The effects of Ang II (1 μM) and/or Losartan (1 μM) for 24 h on pHi recovery rate after acid loading in control and treated podocytes. The values are mean ± SEM of 8–11 / groupBack to article page