Table 1 Baseline patient characteristics
From: Preoperative serum uric acid predicts incident acute kidney injury following cardiac surgery
Variables | Uric acid > median (n = 124) | Uric acid < median (n = 123) | P- Value |
|---|---|---|---|
Serum uric acid (μmol/l; mean ± SD) | 464.94 ± 91.066 | 301.93 ± 45.434 | |
Demographics | |||
Age (yr; mean ± SD) | 67.40 ± 12.221 | 68.26 ± 10.851 | 0.557 |
Female gender (n; %) | 34 (27.4) | 48 (39.0) | 0.053 |
BMI (mean ± SD) | 28.213 ± 4.4752 | 27.089 ± 4.5357 | 0.054 |
Surgery type: n (%) | |||
Valves | 43 (34.7) | 50 (40.7) | 0.335 |
Bypass | 59 (47.6) | 50 (40.7) | 0.275 |
Valves + Bypass | 22 (17.7) | 22 (17.9) | 0.976 |
Other | − | 1 (0.8) | |
Renal function | |||
Serum- Creatinine (μmol/l; mean ± SD) | 101.35 ± 31.794 | 81.89 ± 26.336 | < 0.001 |
CKD- Epi- GFR (mean ± SD) | 66.865 ± 22.0789 | 78.676 ± 18.1805 | < 0.001 |
Comorbidities: n (%) | |||
Hypertension | 114 (91.9) | 110 (89.4) | 0.264 |
CKD | 38 (30.6) | 17 (13.8) | 0.001 |
Diabetes | 41 (33.1) | 27 (21.0) | 0.050 |
PVD | 17 (13.7) | 13 (10.6) | 0.452 |
Congestive heart failure | 94 (75.8) | 89 (72.4) | 0.332 |
COPD | 19 (15.3) | 13 (10.6) | 0.257 |
Previous heart surgery | 16 (12.9) | 9 (7.3) | 0.130 |
Medication: n (%) | |||
ACE- Inhibitor | 67 (54.0) | 62 (50.4) | 0.250 |
AT1- Receptor- Blocker | 16 (12.9) | 17 (13.8) | 0.984 |
Calcium Antagonist | 27 (21.8) | 28 (22.8) | 0.940 |
Βeta- Blocker | 76 (61.3) | 73 (59.3) | 0.371 |
Diuretic | 56 (45.2) | 43 (35.0) | 0.034 |
Lipid- lowering drugs | 51 (41.1) | 54 (43.9) | 0.983 |
Allopurinol | 3 (2.4) | 12 (9.8) | 0.020 |
Intraoperative parameters | |||
Operation time (minutes; mean ± SD) | 213.26 ± 85.004 | 203.81 ± 81.271 | 0.373 |
CPB- time (minutes; mean ± SD) | 104.08 ± 67.311 | 103.31 ± 64.880 | 0.928 |
ACC- time (minutes; mean ± SD) | 60.53 ± 40.365 | 61.31 ± 36.619 | 0.876 |
PRBC (mean ± SD) | 2.30 ± 3.193 | 1.98 ± 2.054 | 0.343 |
FFP (mean ± SD) | 1.44 ± 2.470 | 0.96 ± 1.822 | 0.084 |
Need for reoperation (n; %) | 17 (13.7) | 16 (13.0) | 0.872 |