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Table 1 Baseline patient characteristics

From: Preoperative serum uric acid predicts incident acute kidney injury following cardiac surgery

Variables Uric acid > median (n = 124) Uric acid < median (n = 123) P- Value
Serum uric acid (μmol/l; mean ± SD) 464.94 ± 91.066 301.93 ± 45.434  
Demographics
 Age (yr; mean ± SD) 67.40 ± 12.221 68.26 ± 10.851 0.557
 Female gender (n; %) 34 (27.4) 48 (39.0) 0.053
 BMI (mean ± SD) 28.213 ± 4.4752 27.089 ± 4.5357 0.054
Surgery type: n (%)
 Valves 43 (34.7) 50 (40.7) 0.335
 Bypass 59 (47.6) 50 (40.7) 0.275
 Valves + Bypass 22 (17.7) 22 (17.9) 0.976
 Other 1 (0.8)  
Renal function
 Serum- Creatinine (μmol/l; mean ± SD) 101.35 ± 31.794 81.89 ± 26.336 < 0.001
 CKD- Epi- GFR (mean ± SD) 66.865 ± 22.0789 78.676 ± 18.1805 < 0.001
Comorbidities: n (%)
 Hypertension 114 (91.9) 110 (89.4) 0.264
 CKD 38 (30.6) 17 (13.8) 0.001
 Diabetes 41 (33.1) 27 (21.0) 0.050
 PVD 17 (13.7) 13 (10.6) 0.452
 Congestive heart failure 94 (75.8) 89 (72.4) 0.332
 COPD 19 (15.3) 13 (10.6) 0.257
 Previous heart surgery 16 (12.9) 9 (7.3) 0.130
Medication: n (%)
 ACE- Inhibitor 67 (54.0) 62 (50.4) 0.250
 AT1- Receptor- Blocker 16 (12.9) 17 (13.8) 0.984
 Calcium Antagonist 27 (21.8) 28 (22.8) 0.940
 Βeta- Blocker 76 (61.3) 73 (59.3) 0.371
 Diuretic 56 (45.2) 43 (35.0) 0.034
 Lipid- lowering drugs 51 (41.1) 54 (43.9) 0.983
 Allopurinol 3 (2.4) 12 (9.8) 0.020
Intraoperative parameters
 Operation time (minutes; mean ± SD) 213.26 ± 85.004 203.81 ± 81.271 0.373
 CPB- time (minutes; mean ± SD) 104.08 ± 67.311 103.31 ± 64.880 0.928
 ACC- time (minutes; mean ± SD) 60.53 ± 40.365 61.31 ± 36.619 0.876
 PRBC (mean ± SD) 2.30 ± 3.193 1.98 ± 2.054 0.343
 FFP (mean ± SD) 1.44 ± 2.470 0.96 ± 1.822 0.084
 Need for reoperation (n; %) 17 (13.7) 16 (13.0) 0.872
  1. BMI Body mass index, CKD- Epi- GFR Chronic Kidney Disease Epidemiology Collaboration Glomerular Filtration Rate, CKD Chronic Kidney Disease, PVD Peripheral Vascular Disease, COPD Chronic Obstructive Pulmonary Disease, ACE  Angiotensin- converting Enzyme, AT1- Receptor- Blocker Angiotensin- 1- Receptor- Blocker, CPB Cardiopulmonary Bypass, ACC Aortic Cross Clamp, PRBC Packed Red Blood Cells, FFP Fresh Frozen Plasma