Skip to main content

Table 1 Baseline characteristics of 160 patients with AAV

From: Neutrophil to lymphocyte ratio at diagnosis can estimate vasculitis activity and poor prognosis in patients with ANCA-associated vasculitis: a retrospective study

Variables

Values

Variants of AAV

 MPA

85 (53.1)

 GPA

41 (25.6)

 EGPA

34 (21.3)

Demographic data at diagnosis

 Age (year old)

55.2 ± 15.1

 Male gender (N, (%))

48 (30.0)

ANCA at diagnosis (N, (%))

 MPO-ANCA (or P-ANCA)

99 (61.9)

 PR3-ANCA (or C-ANCA)

27 (16.9)

 MPO-ANCA (or P-ANCA) and PR3-ANCA (or C-ANCA)

7 (4.4)

 ANCA negative

41 (25.6)

Clinical manifestations at diagnosis (N, (%))

 General

71 (44.4)

 Cutaneous

37 (23.1)

 Mucous membranes/eyes

12 (7.5)

 Ear Nose Throat (ENT)

56 (35.0)

 Chest

84 (52.5)

 Cardiovascular

45 (28.1)

 Abdominal

10 (6.3)

 Renal

95 (59.4)

 Nervous system

52 (32.5)

Vasculitis activity and prognostic factors at diagnosis

 BVAS or BVAS for GPA

11.9 ± 7.6

 FFS (2009)

1.3 ± 1.0

Laboratory results at diagnosis

 WBC (/mm3)

10,175.6 ± 4758.2

 Neutrophil (/mm3)

7227.5 ± 4047.2

 Lymphocyte (/mm3)

1564.0 ± 721.2

 Platelet (×1,000/mm3)

327.5 ± 141.9

 ESR (mm/hr)

60.1 ± 37.4

 CRP (mg/L)

43.0 ± 56.5

NLR at diagnosis

6.6 ± 8.3

Prognosis

 Follow-up duration (months)

55.6 ± 51.5

 Relapse (N, (%))

43 (26.9)

 Death (N, (%))

14 (8.8)

  1. Values are expressed as mean and standard deviation or N (%)
  2. AAV antineutrophil associated vasculitis, MPA microscopic polyangiitis, GPA granulomatosis with polyangiitis, EGPA eosinophilic granulomatosis with polyangiitis, MPO myeloperoxidase, ANCA antineutrophil cytoplasmic antibody, P-ANCA perinuclear ANCA, PR3 proteinase 3, C-ANCA cytoplasmic ANCA, BVAS Birmingham vasculitis activity score, FFS five factor score, WBC white blood cell, ESR erythrocyte sedimentation rate, CRP C-reactive protein, NLR neutrophil to lymphocyte ratio