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Table 1 Baseline characteristics of 160 patients with AAV

From: Neutrophil to lymphocyte ratio at diagnosis can estimate vasculitis activity and poor prognosis in patients with ANCA-associated vasculitis: a retrospective study

Variables Values
Variants of AAV
 MPA 85 (53.1)
 GPA 41 (25.6)
 EGPA 34 (21.3)
Demographic data at diagnosis
 Age (year old) 55.2 ± 15.1
 Male gender (N, (%)) 48 (30.0)
ANCA at diagnosis (N, (%))
 MPO-ANCA (or P-ANCA) 99 (61.9)
 PR3-ANCA (or C-ANCA) 27 (16.9)
 MPO-ANCA (or P-ANCA) and PR3-ANCA (or C-ANCA) 7 (4.4)
 ANCA negative 41 (25.6)
Clinical manifestations at diagnosis (N, (%))
 General 71 (44.4)
 Cutaneous 37 (23.1)
 Mucous membranes/eyes 12 (7.5)
 Ear Nose Throat (ENT) 56 (35.0)
 Chest 84 (52.5)
 Cardiovascular 45 (28.1)
 Abdominal 10 (6.3)
 Renal 95 (59.4)
 Nervous system 52 (32.5)
Vasculitis activity and prognostic factors at diagnosis
 BVAS or BVAS for GPA 11.9 ± 7.6
 FFS (2009) 1.3 ± 1.0
Laboratory results at diagnosis
 WBC (/mm3) 10,175.6 ± 4758.2
 Neutrophil (/mm3) 7227.5 ± 4047.2
 Lymphocyte (/mm3) 1564.0 ± 721.2
 Platelet (×1,000/mm3) 327.5 ± 141.9
 ESR (mm/hr) 60.1 ± 37.4
 CRP (mg/L) 43.0 ± 56.5
NLR at diagnosis 6.6 ± 8.3
Prognosis
 Follow-up duration (months) 55.6 ± 51.5
 Relapse (N, (%)) 43 (26.9)
 Death (N, (%)) 14 (8.8)
  1. Values are expressed as mean and standard deviation or N (%)
  2. AAV antineutrophil associated vasculitis, MPA microscopic polyangiitis, GPA granulomatosis with polyangiitis, EGPA eosinophilic granulomatosis with polyangiitis, MPO myeloperoxidase, ANCA antineutrophil cytoplasmic antibody, P-ANCA perinuclear ANCA, PR3 proteinase 3, C-ANCA cytoplasmic ANCA, BVAS Birmingham vasculitis activity score, FFS five factor score, WBC white blood cell, ESR erythrocyte sedimentation rate, CRP C-reactive protein, NLR neutrophil to lymphocyte ratio