Neutrophil to lymphocyte ratio at diagnosis can estimate vasculitis activity and poor prognosis in patients with ANCA-associated vasculitis: a retrospective study

Table 2 Univariable and multivariable linear regression analyses of BVAS and variables related to the inflammatory burdens in 160 patients with AAV

	Univariable analysis			Multivariable analysis (ESR, CRP and Lymphocyte)			Multivariable analysis (ESR, CRP and NLR)
	Regression Coefficient (Crude B)	Correlation Coefficient (R = β)	P value	Standardized β^*	95% confidence interval	P value	Standardized β^*	95% confidence interval	P value
Demographic data at diagnosis
Age (years old)	0.027	0.053	0.504
Laboratory data at diagnosis
WBC (/mm³)	0.000	0.095	0.232
Neutrophil (/mm³)	0.000	0.114	0.150
Lymphocyte (/mm³)^*	− 0.002	−0.198	0.012	−0.160	− 0.003, 0.000	0.045	N/A	N/A	N/A
Platelet (×1,000/mm³)	0.003	0.060	0.449
ESR (mm/hr)	0.044	0.218	0.006	0.167	−0.003, 0.071	0.074	0.177	−0.001, 0.073	0.058
CRP (mg/L)	0.023	0.169	0.033	0.044	−0.019, 0.031	0.644	0.029	−0.021, 0.029	0.757
NLR	0.187	0.204	0.009	N/A	N/A	N/A	0.169	0.010, 0.299	0.036

^*We performed multivariable linear regression analyses of ESR and CRP with either lymphocyte count or NLR
BVAS Birmingham vasculitis activity score, AAV antineutrophil associated vasculitis, ESR erythrocyte sedimentation rate, CRP C-reactive protein, WBC white blood cell, NLR neutrophil to lymphocyte ratio

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