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Table 2 Findings of both groups according to kidney function in patients with GUTB

From: Chronic kidney disease with genitourinary tuberculosis: old disease but ongoing complication

Variables

Normal kidney function group (n = 45)

CKD group (n = 11)

Total (n = 56)

p

Diagnosis

 Positivity of urine AFB stain

3/41 (7.3)

3/10 (30.0)

6/51 (11.8)

0.081

 Positivity of urinary TB culture

17/38 (44.7)

7/10 (70.0)

24/48 (50.0)

0.155

 Positivity of urine TB PCR study

17/36 (47.2)

8/9 (88.9)

25/45 (55.6)

0.030

 Histopathologic diagnosis

24 (53.3)

6 (54.5)

30/55 (53.6)

0.741

Laboratory data

 White blood cell (/μl)

6880 (5650–7890)

6520 (5580–8395)

6695 (5580–7915)

0.699

 Hemoglobin (g/dl)

12.5 ± 1.8

11.7 ± 1.7

12.3 ± 1.8

0.174

 Platelet (103/μl)

259.0 ± 80.5

263.2 ± 121.2

259.9 ± 89.1

0.893

 ESR (mm/hr)

46.9 ± 23.8

82.5 ± 53.0

53.4 ± 30.7

0.145

 Blood urea nitrogen (mg/dl)

13.9 (10.5–16.9)

17.8 (15.4–27.8)

14.4 (11.6–17.6)

0.006

 Creatinine (mg/dl)

0.9 (0.8–1.0)

1.4 (1.1–1.8)

1.0 (0.8–1.1)

0.002

 eGFR (MDRD)

78.1 ± 16.5

49.4 ± 23.4

75.8 ± 23.5

0.002

 eGFR (MDRD) after 1 year

82.7 ± 16.5

35.1 ± 18.1

72.8 ± 25.6

< 0.001

 Acute renal failure

3 (6.7)

7 (63.6)

10 (17.9)

< 0.001

 Glucose (mg/dl)

98.0 (89.0–108.0)

104.0 (99.5–121.5)

100.0 (90.0–112.0)

0.075

 Albumin (g/dl)

4.4 (3.9–4.6)

3.8 (3.5–4.2)

4.3 (3.8–4.5)

0.102

 CRP (mg/dl)

10.2 (3.7–38.2)

45.3 (19.3–65.5)

15.0 (5.0–44.2)

0.090

 Microscopic hematuria

19 (42.2)

9 (81.8)

28 (50.0)

0.019

 Gross hematuria

14 (31.1)

5 (45.5)

19 (33.9)

0.481

 Pyuria

29 (64.4)

8 (72.7)

37 (66.1)

0.732

 Proteinuria

6 (13.3)

5 (45.5)

11 (19.6)

0.029

  1. Bold values indicate statistically significant differences
  2. Data were presented as mean ± SD, number (percentage) or median (IQR). All data are based on the results at the time of diagnosis except for ‘eGFR after 1 year’
  3. GUTB genitourinary tuberculosis, CKD chronic kidney disease, AFB acid-fast bacilli, TB tuberculosis, PCR polymerase chain reaction, ESR erythrocyte sedimentation rate, eGFR estimated glomerular filtration rate, MDRD Modification of Diet in Renal Disease study equation, CRP c-reactive protein, SD standard deviation, IQR interquartile range