Table 1 Baseline characteristics of the subjects at the time of the renal biopsy
Characteristic | Whole G3–4 | CKD G stage | Treatment | |||||
|---|---|---|---|---|---|---|---|---|
G3a | G3b | G4 | Pulse (SP) | Oral (OS) | None (NS) | |||
n | 764 | 397 | 236 | 131 | 121 | 139 | 506 | |
Age, years | 50.3 ± 13.6 | 47.7 ± 13.8 | 52.3 ± 13.4 | 54.6 ± 12.8 | 49.3 ± 14.7 | 49.5 ± 13.2 | 50.8 ± 13.4 | |
Gender | ||||||||
Female | 319 (42) | 171 (57) | 90 (38) | 58 (44) | 45 (37) | 53 (38) | 221 (44) | |
Male | 445 (58) | 226 (43) | 146 (62) | 73 (56) | 76 (63) | 86 (62) | 283 (56) | |
Follow-up, months | 70 ± 115 | 86 ± 141 | 65 ± 103 | 44 ± 61 | 67 ± 81 | 88 ± 125 | 65 ± 121 | |
eGFR, ml/min/1.73m2 | 43 ± 12 | 53 ± 4.2 | 38 ± 5.6 | 23 ± 4.5 | 41 ± 13 | 41 ± 13 | 44 ± 11 | |
CKD G Stage | ||||||||
G3a | 397 (52) | 397 (100) | – | – | 56 (46) | 64 (46) | 277 (55) | |
G3b | 236 (31) | – | 236 (100) | – | 38 (31) | 45 (32) | 153 (30) | |
G4 | 131 (17) | – | – | 131 (100) | 27 (22) | 30 (22) | 74 (15) | |
UP, g/gCr | 0.95 ± 1.4 | 0.70 ± 1.1 | 1.2 ± 1.7 | 1.8 ± 2.7 | 1.5 ± 1.9 | 1.8 ± 2.2 | 0.73 ± 1.1 | |
< 1.0 | 385 (50) | 248 (62) | 94 (40) | 43 (33) | 47 (39) | 45 (32) | 309 (61) | |
≥ 1.0 | 363 (48) | 141 (36) | 136 (58) | 86 (66) | 74 (61) | 94 (68) | 195 (39) | |
sBP, mmHg | 134 ± 19 | 129 ± 19 | 137 ± 20 | 140 ± 19 | 134 ± 17 | 135 ± 19 | 133 ± 20 | |
dBP, mmHg | 80 ± 13 | 78 ± 12 | 82 ± 13 | 83 ± 14 | 79 ± 12 | 80 ± 13 | 80 ± 13 | |
RAAs inhibition | ||||||||
+ | 209 (27) | 104 (26) | 70 (30) | 34 (26) | 62 (51) | 55 (40) | 92 (18) | |
- | 313 (41) | 173 (44) | 85 (36) | 55 (42) | 59 (49) | 83 (60) | 172 (34 | |
Corticosteroids | ||||||||
Pulse (SP) | 121 (16) | 56 (14) | 38 (16) | 27 (21) | 121 (100) | – | – | |
Oral (OS) | 139 (18) | 64 (16) | 45 (19) | 30 (23) | – | 139 (100) | – | |
None (NS) | 506 (66) | 277 (70) | 153 (65) | 74 (56) | – | – | 506 (100) | |
Immunosuppressant | ||||||||
+ | 10 (2) | 4 (1) | 5 (2) | 1 | (1) | 4 (3) | 6 (4) | 0 (0) |
- | 513 (70) | 274 (69) | 151 (64) | 88 | (67) | 117 (97) | 132 (95) | 264 (52) |
NA | 241 (28) | 119 (30) | 80 (34) | 42 | (32) | 0 (0) | 1 (1) | 240 (48) |
Tonsillectomy | 80 (10) | 46 (12) | 26 (11) | 8 | (6) | 68 (56) | 4 (3) | 8 (2) |