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Table 2 Nutritional data and functional data of patients with renal disease according to stage of renal disease (CKD chronic kidney disease; ESRD-HD end-stage renal disease treated with hemodialysis; renal transplant: recipients of a renal transplant)

From: High rates of central obesity and sarcopenia in CKD irrespective of renal replacement therapy – an observational cross-sectional study

 

CKD

N = 112

ESRD-HD

N = 24

Renal transplant

N = 72

P (ANOVA) Kruskal Wallis test

Weight (kg)

82.1 ± 18.6

72.5 ± 12.4

79.0 ± 15.0

0.04

BMI (kg/m2)

27.8 ± 5.1

24.7 ± 3.7

26.7 ± 4.5

0.02

Resistance (Ω)

475 ± 80

509 ± 67

487 ± 86

0.104

Reactance (Ω)

48 ± 11

45 ± 14

50 ± 13

0.215

Phase angle (°)

5.76 ± 1.19

5.0 ± 1.4

5.86 ± 1.03

0.027

Appendicular lean mass (kg)a

21.3 ± 5.2

19.6 ± 5.3

21.4 ± 4.8

0.274

Skeletal muscle index (ALM/Ht2, kg/m2)b

7.1 (6.3, 7.6)

6.6 (5.7, 7.6)

7.6 (6.2, 8.0)

0.077

Fat mass (kg)

Fat mass (% of weight)

27.4 (19.8, 35.1)

33.6 (27.4, 39.1)

22.4 (13.9, 27.1)

29.0 (21.4, 34.5)

25.2 (15.9, 34.8)

32.9 (23.4, 41.1)

0.102

0.256

Fat free mass (kg)

53.3 (45.8, 61.6)

49.5 (44.9, 54.8)

55.2 (43.3, 59.9)

0.385

Waist circumference (cm)

99.2 ± 14.4

95.9 ± 13.6c

98.0 ± 14.3

0.47

Mid upper arm circumference (cm)

32.6 ± 4.8

29.0 ± 3.6

30.5 ± 3.4

< 0.001

Biceps skinfold (mm)

15 (10, 21)

8 (4, 11)

7 (5, 12)

< 0.001

Triceps skinfold (mm)

23 (17, 30)

14 (10, 19)

18 (12, 26)

< 0.001

Dietary intake (Kcal/d)

1730 (1380, 2120)

1700 (1230, 1927)

1794 (1303, 2087)

0.635

Dietary intake (Kcal/kg bw/d)

22 (16, 29)

23 (17, 30)

21 (18, 28)

0.875

Dietary protein (g/d)

76 (56, 96)

71 (60, 80)

78 (59, 103)

0.238

Dietary protein (g/kg bw/d)

0.95 (0.73, 1.23)

1.00 (0.77, 1.23)

0.96 (0.79, 1.38)

0.493

Handgrip strength average (kg)

30 ± 12

28 ± 12

30 ± 11

0.66

Handgrip strength maximum (kg)

32 ± 13

31 ± 13

32 ± 11

0.75

Knee extension average (N)

173 ± 52

183 ± 37

0.234

Knee extension maximum (N)

184 ± 54

195 ± 39

0.235

Nutritonal risk (NRS2002)

3 (3%)

8 (33%)

5 (7%)

< 0.001

Sarcopeniad

41 (37%)

10 (42%)

23 (32%)

0.642

Central obesity

58 (53%)

9 (39%)c

35 (50%)

0.490

  1. Data are shown as median with interquartile range or as mean with standard deviation
  2. aappendicular lean mass was calculated according to MacDonald et al. [10]
  3. bSkeletal mass index calculated from appendicular lean mass divided by height squared
  4. cn = 23
  5. dBIA measurements were performed in 101 CKD patients, 23 ESRD-HD patients and 69 renal transplant patients due to contraindications present. In patients with missing BIA measurements, sarcopenia was defined by low hand grip strength only