Table 1 Demographic, clinical and laboratory data among survivors and non-survivors
Total | Survivors | Non-survivors | p | |
|---|---|---|---|---|
Patients, % | 258 | 185 (71.7) | 73 (28.4) | |
Age, years (median, IQR) | 59 (52;65) | 57.9 (12.2) | 58.7 (12.2) | 0.681 |
Gender, male / female (%) | 185 (71.7) / 73 (28.3) | 130 (70.3) / 55 (75.3) | 55 (29.7) / 18 (24.7) | 0.447 |
Etiology, n (%) | ||||
Alcohol | 125 (48.4) | 93 (50.3) | 32 (43.8) | 0.407 |
Viral | 100 (38.8) | 68 (36.8) | 32 (43.8) | 0.322 |
Non-viral and Non-alcohol | 54 (20.9) | 40 (21.6) | 14 (19.2) | 0.736 |
Days of hospitalization (median, IQR) | 7 (3;13) | 6 (3;11) | 12 (6;23) | < 0.001 |
ICU admission (%) | 78 (30.2) | 35 (18.9) | 43 (58.9) | < 0.001 |
admission MELD score (median, IQR) | 18 (14;23) | 17 (13;22) | 19 (16;26) | 0.002 |
admission APACHE II (median, IQR) | 16 (12;22) | 15 (12;20) | 18 (14;23) | 0.015 |
admission MAP (mmHg), (median, IQR) | 89 (75;100) | 91 (74;102) | 84 (76;95) | 0.036 |
Comorbidities, n (%) | ||||
Hypertension | 114 (44.2) | 88 (47.6) | 26 (35.6) | 0.095 |
Diabetes | 82 (31.8) | 67 (36.2) | 15 (20.5) | 0.017 |
Smoking (present or past) | 69 (26.7) | 46 (24.9) | 23 (31.5) | 0.279 |
Cancer | 57 (22.1) | 32 (17.3) | 25 (34.2) | 0.004 |
Hepatocarcinoma | 41 (70.7) | 24 (72.7) | 17 (68) | 0.775 |
Non-hepatocarcinoma | 17 (29.3) | 9 (27.3) | 8 (32) | |
Heart failure | 26 (10.1) | 20 (10.8) | 6 (8.2) | 0.649 |
Cause of hospitalization, n (%) | ||||
Infection | 138 (53.5) | 92 (66.7) | 46 (33.3) | 0.071 |
Non-infection | 120 (46.5) | 93 (77.5) | 27 (22.5) | |
AKI, n (%) | ||||
Yes | 139 (53.9) | 80 (57.6) | 59 (42.4) | < 0.001 |
No | 119 (46.1) | 105 (82.2) | 14 (11.8) | |
Progression of AKI, n (%) | ||||
Yes | 39 (27.9) | 16 (41) | 23 (59) | < 0.001 |
No | 101 (72.1) | 77 (76.2) | 24 (23.8) | |
Baseline eGFR (ml/min/1.73m2) (median, IQR) | 57 (35;80) | 59 (37;82) | 52 (31;72) | 0.055 |
Laboratory | ||||
Hemoglobin, g/dL (mean, SD) | 11.2 (2.75) | 11.2 (2.7) | 11.1 (2.8) | 0.894 |
Albumin, g/dL (mean, SD) | 2.9 (0.6) | 3 (0.6) | 2.7 (0.6) | 0.008 |
Leucocytes, 1000/uL (median, IQR) | 8.8 (5.7;12.4) | 8.1 (5.4;11.0) | 10.7 (7.3;14.1) | < 0001 |
Platelets, 1000/uL (median, IQR) | 126 (80;186) | 122 (74;180) | 143 (94;195) | 0.158 |
INR (median, IQR) | 1.4 (1.2;1.6) | 1.4 (1.2;1.6) | 1.5 (1.3;1.7) | 0.022 |
Total Bilirrubin, mg/dL (median, IQR) | 2.2 (1.0;4.7) | 1.7 (0.8;3.5) | 2.9 (1.2;7.6) | 0.002 |
Baseline Creatinine, mg/dL (median, IQR) | 1.04 (0.80; 1.58) | 1.02 (0.76;1.50) | 1.10 (0.87;1.74) | 0.054 |
Admission Creatinine, mg/dL (median,IQR) | 1.40 (0.85; 2.34) | 1.24 (0.80; 2.31) | 1.61 (0.96; 2.50) | 0.086 |
Peak Creatinine, mg/dL (median, IQR) | 1.9 (1.01; 2.98) | 1.47 (0.92; 2.48) | 2.86 (1.93; 4.10) | < 0.001 |
Sodium mEq/L (median, IQR) | 136 (132; 139) | 137 (133;139) | 136 (132;139) | 0.197 |
Urea, mg/dL (median, IQR) | 61 (34;99) | 52 (33;89) | 76 (38;104) | 0.022 |