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Fig. 1 | BMC Nephrology

Fig. 1

From: The efficacy and safety of anti-interleukin-6 receptor monoclonal blockade in a renal transplant patient with Castleman disease: early post-transplant outcome

Fig. 1

Histology and immunostaining. Specimens obtained from the inguinal lymph node, lung and kidney. a A microscopic examination of the inguinal lymph node revealed interfollicular expansion with plasmacytosis, compatible with plasma cell-type MCD. Numerous IgA- and IL-6-positive cells were detected. b A lung biopsy shows prominent infiltration of plasma cells with IgA- and IL-6-positivity. c Periodic acid-Schiff staining and Masson trichrome staining show ESRD; the stained blue area is the fibrous tissue in the ESRD kidney. Immunofluorescence staining of a renal biopsy specimen shows granular staining for IgA in the mesangium

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