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Table 1 Clinical characteristics of all enrolled patients at the onset of cyst infection

From: Cyst infection in autosomal dominant polycystic kidney disease: penetration of meropenem into infected cysts

Patient number

1

2

3

4

5

6

7

8

9

10

Total (mean ± SD)

Gender (M/F)

M

F

F

F

F

M

F

F

M

M

10 (4/6)

Age (years)

62

84

47

67

62

61

70

79

63

63

65.8 ± 8.9

Renal function

On dialysis

On dialysis

On dialysis

On dialysis

On dialysis

Serum Cr 0.88 mg/dL

On dialysis

On dialysis

On dialysis

On dialysis

Dialysis 9

Non dialysis 1

Body weight (kg)

61.4

42.7

51.5

51.1

41.4

59.9

47.1

48.1

55.8

66

52.5 ± 8.2

Total kidney volume (cm3)

4878.9

1696.1

1193.9

559.1

3429.6

8284.4

905.8

1386.0

1992.1

4498.7

2882.5 ± 2419

Liver volume (cm3)

5173.4

1527.9

4651.3

2903.0

2661.9

8965.7

2235.9

8340.5

4339.8

850.0

4164.9 ± 2734

Number of prior cyst infections

3

6

2

4

1

3

18

0

3

12

5.2 ± 5.6

Site of infected cyst

Liver

Liver

Liver

Liver

Liver

Liver

Liver

Liver

Kidney

Kidney

Liver 8

Kidney 2

Maximum body temperature (°C)

40.0

39.0

38.0

38.5

38.4

39.0

38.7

39.0

39.9

39.0

38.6 ± 1.3

Abdominal pain/flank pain/back pain

Flank pain

Epigastric pain

Right hypochondralgia

Epigastric pain

None

Epigastric pain

Epigastric pain

Right hypochondralgia

none

None

 

Pyuria

None

None

None

None

None

None

None

None

None

None

 

Blood culture test

E.coli

N

N

N

N

E-coli

N

N

E-coli

N

Negative 7

Cyst content culture test

N

N

N

N

N

N

N

N

N

N

Negative 10

Blood test

 Maximum WBC (/μL)

7050

6900

8500

11,400

7900

14,400

8800

8100

7100

7800

8795 ± 2358

 Hb (g/dL)

10.0

9.6

10.5

7.7

10.1

8.6

9.4

9.8

9.6

11

9.6 ± 0.9

 Total protein (g/dL)

8

4.9

7.4

6.9

7.3

8.2

6.9

7.7

7.4

6.6

7.1 ± 0.9

 Alb (g/dL)

2.5

1.8

2.7

2.3

3.1

2.4

2.5

1.9

2.5

3.2

2.5 ± 0.4

 GOT (IU/L)

14

7

15

9

16

29

18

17

19

12

15.6 ± 6.1

 GPT (IU/L)

2

2

4

3

6

32

17

2

5

2

7.5 ± 9.7

 ChE (IU/L)

122

192

272

245

  

158

60

214

199

195.5 (131, 237.3)a

 ALP (IU/L)

392

277

199

290

613

720

499

273

359

260

324.5 (269, 527)a

 γGTP (IU/L)

46

51

66

47

72

154

73

44

69

31

58.5 (45.5, 72.3)a

 CRP (mg/dL)

21.84

20.90

21.20

8.9

21.4

16.0

26.9

10.7

15.50

12.8

18.5 (12.3, 21.5)a

  1. SD standard deviation, IQR interquartile range (25–75%), N Negative, NA not applicable
  2. a[median (IQR)]