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Table 2 MEPM concentration in serum and cyst fluid

From: Cyst infection in autosomal dominant polycystic kidney disease: penetration of meropenem into infected cysts

Patient number

1

2

3

4

5

6

7

8

9

10

Total (mean ± SD)

Cyst number

1

2

3

4

5

6a

6b

7a

7b

8a

8b

8c

9

10

 

Time between MEPM administration and cyst drainage (min.)

35

30

63

50

72

54

65

21

75

178

202

222

75

178

95.1 ± 70.5

Fluid volume aspirated from cysts (mL)

75

10

135

12

100

25

5

55

40

75

130

75

40

75

57.3 ± 44.0

MEPM serum concentration (μg/mL)

27.7

41.8

40.4

24.4

59.2

19.7

47.3

32.5

24.2

34.3

35.2 ± 12.2

MEPM cyst fluid concentration (μg/mL)

0.4

6.7

7.3

0.7

0.1

2.7

3.7

6.0

3.2

1.3

1.6

2.6

3.2

1.3

3.0 ± 2.6

MEPM concentration ratio (cyst content/serum) (%)

1.44

16.0

18.1

2.9

0.2

13.7

18.8

12.7

13.2

3.8

4.9

8

13.2

3.8

9.46 ± 7.2