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Table 5 Comparison of survival on CRRT by principal diagnosis, weight, CRRT indication, and immune status between study eras and shown over the 10 year study period

From: Pediatric continuous renal replacement therapy: have practice changes changed outcomes? A large single-center ten-year retrospective evaluation

 

2004–2008

2009–2013

2004–2013

Survivor

n (%)

Survivor

n (%)

Survivor

n (%)

Principal Diagnosis Category

 Cardiac

7 (54%)

3 (27%)

10 (42%)

 Renal

4 (44%)

14 (74%)

18 (64%)

 Liver

6 (32%)

17 (46%)

23 (41%)

 Hematology/Oncology a

10 (56%)

3 (18%)

13 (37%)

 Bone marrow transplant

3 (17%)

5 (33%)

8 (24%)

 Pulmonary

4 (36%)

2 (50%)

6 (40%)

 Inborn error of metabolism

5 (100%)

7 (70%)

12 (80%)

 Sepsis

3 (30%)

2 (40%)

5 (33%)

 Neonates

8 (80%)

8 (62%)

16 (70%)

 Other b

10 (63%)

10 (77%)

20 (69%)

Weight

 0-10 kg

9 (35%)

19 (50%)

28 (44%)

 10-25 kg

13 (45%)

22 (56%)

35 (51%)

 25-50 kg

17 (49%)

13 (39%)

30 (44%)

 > 50 kg

21 (54%)

17 (50%)

38 (52%)

Indications for CRRT

 Fluid overload

31 (42%)

35 (49%)

66 (46%)

 Fluid overload & electrolyte management

12 (43%)

17 (41%)

29 (41%)

 Prevent fluid overload/provide nutrition

3 (50%)

2 (67%)

5 (56%)

 Electrolyte management

4 (57%)

4 (44%)

8 (50%)

 Other c

10 (71%)

13 (68%)

23 (70%)

Days on CRRT

 1 day

8 (47%)

5 (55%)

12 (50%)

 2–7 days

24 (42%)

34 (45%)

58 (44%)

 8–14 days

18 (50%)

12 (36%)

30 (43%)

 15–21 days

10 (53%)

11 (48%)

21 (50%)

 22–28 days

1 (17%)

7 (50%)

8 (40%)

 > 28 days

3 (25%)

7 (50%)

10 (38%)

Immune Status

 Solid organ transplant

11 (44%)

17 (52%)

28 (48%)

 Bone marrow transplant

5 (29%)

5 (36%)

10 (32%)

 Other immunocompromised

12 (48%)

11 (42%)

23 (45%)

 Not immunocompromised

32 (52%)

38 (54%)

70 (53%)

  1. ap < 0.05 comparing 2004–2008 survivors with 2009–2013 survivors
  2. bIncludes rheumatologic, gastroenterologic, multiple organ, neurologic, ingestions, hemorrhage, rhabdomyolysis, and non-accidental trauma
  3. cIncludes hemodynamic instability, hyperammonemia, ingestion, and end-stage renal disease