Low birth weight associates with glomerular area in young male IgA nephropathy patients

BMC Nephrology

Table 4 Linear associations between glomerular area and birth related and clinical characteristics, Norway (1988–2013)

	Model 1 β-coefficient^a	p-value	Model 2 β-coefficient^b	p-value
Birthweight (Kg)	− 1143	0.06	−1357	0.01
Gestational age (Weeks)	− 141	0.3	−198	0.1
Birth weight for gestational age (Z-score)	− 711	0.08	− 521	0.2
Maternal preeclampsia (Yes/No)	4305	0.02	3577	0.046
Gender (male vs female)	1736	0.05	1849	0.03
Age at biopsy (10 years)^c	1368	0.007	1418	0.04
Body weight at biopsy (10 kg)^c	668	0.004	491	0.1
Body mass index at biopsy (kg/m²)	238	0.02	141	0.6
eGFR (10 ml/min/1.73m²)^c	− 530	0.01	− 297	0.1
Systolic BP (10 mmHg)^c	159	0.5	− 164	0.54
Urinary Protein (g/d)	132	0.7	154	0.6

^a Model 1 adjusted for IgA nephropathy diagnosis at biopsy
^bModel 2 adjusted for IgA nephropathy diagnosis at biopsy, gender and age at biopsy
^c Body weight at time of biopsy, eGFR and systolic BP are given per 10 unit increase to give meaningful coefficients, otherwise one unit was used for other variables

ISSN: 1471-2369