Table 4 Antibiotic susceptibility profiles of VS isolates from VS peritonitis episodes in patients undergoing peritoneal dialysis
Tested antibiotic | VS isolates in mono-VS peritonitis, no./No. (%) | VS isolates in mixed-VS peritonitis, no./No. (%) | P | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Susceptible | Non-susceptible | Susceptible | Non-susceptible | |||||||||||
Recent antibiotic exposure (A) | Prior peritonitis (B) | Recent antibiotic exposure (C) | Prior peritonitis (D) | Recent antibiotic exposure (E) | Prior peritonitis (F) | Recent antibiotic exposure (G) | Prior peritonitis (H) | A vs. C | B vs. D | E vs. G | F vs. H | A vs. E | B vs. F | |
Ampicillin | 11/73 (15.1) | 37/73 (50.7) | 1/5 (20.0) | 3/5 (60.0) | 3/28 (10.7) | 19/28 (67.9) | 1/3 (33.3) | 3/3 (100.0) | 0.577 | 1.000 | 0.349 | 0.537 | 0.806 | 0.120 |
Clindamycin | 10/67 (15.0) | 34/67 (50.7) | 2/11 (18.2) | 6/11 (54.5) | 4/29 (13.8) | 20/29 (69.0) | 0/2 (0.0) | 2/2 (100.0) | 1.000 | 0.815 | 1.000 | 1.000 | 1.000 | 0.098 |
Ceftriaxone | 8/62 (13.0) | 30/62 (48.4) | 2/6 (33.3) | 4/6 (66.7) | 1/27 (3.7) | 18/27 (66.7) | 3/4 (75.0) | 4/4 (100.0) | 0.212 | 0.669 | 0.003 | 0.295 | 0.347 | 0.112 |
Erythromycin | 8/57 (14.0) | 27/57 (47.4) | 4/21 (19.0) | 13/21 (61.9) | 3/26 (11.5) | 18/26 (69.2) | 1/5 (20.0) | 4/5 (80.0) | 0.849 | 0.255 | 0.525 | 1.000 | 1.000 | 0.064 |
Penicillin | 10/71 (14.1) | 36/71 (50.7) | 2/7 (28.6) | 4/7 (57.1) | 3/27 (11.1) | 18/27 (66.7) | 1/4 (25.0) | 4/4 (100.0) | 0.642 | 1.000 | 0.442 | 0.435 | 0.957 | 0.156 |
Teicoplanin | 12/74 (16.2) | 39/74 (52.7) | 0/0 (0.0) | 0/0 (0.0) | 4/29 (13.8) | 22/29 (75.9) | 0/0 (0.0) | 0/0 (0.0) | – | – | – | – | 0.998 | 0.031 |
Vancomycin | 11/66 (16.7) | 33/66 (50.0) | 0/0 (0.0) | 0/0 (0.0) | 4/31 (12.9) | 22/31 (71.0) | 0/0 (0.0) | 0/0 (0.0) | – | – | – | – | 0.860 | 0.052 |