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Table 3 Hazard ratios of end-stage renal disease according to the echocardiographic parameters

From: Systolic and diastolic dysfunction affects kidney outcomes in hospitalized patients

  

Univariate

Multivariatea

Parameters

 

HR (95% CI)

P

HR (95% CI)

P

Ejection fraction

4th quartile (n = 355)

1 (Reference)

 

1 (Reference)

 
 

3rd quartile (n = 322)

0.22 (0.026–1.881)

0.167

0.26 (0.067–1.027)

0.055

 

2nd quartile (n = 322)

1.51 (0.478–4.749)

0.484

0.79 (0.226–2.746)

0.708

 

1st quartile (n = 318)

1.33 (0.405–4.348)

0.641

0.12 (0.013–1.093)

0.060

E/e’

1st quartile (n = 328)

1 (Reference)

 

1 (Reference)

 
 

2nd quartile (n = 338)

0.64 (0.107–3.828)

0.624

2.31 (0.171–31.098)

0.528

 

3rd quartile (n = 338)

0.64 (0.106–3.806)

0.620

0.94 (0.076–11.629)

0.961

 

4th quartile (n = 323)

4.13 (1.165–14.635)

0.028

5.20 (0.548–49.273)

0.151

Combined parameterb

1st group (n = 537)

1 (Reference)

 

1 (Reference)

 
 

2nd group (n = 466)

1.55 (0.347–6.930)

0.566

1.44 (0.234–8.819)

0.695

 

3rd group (n = 138)

4.09 (0.825–20.258)

0.085

4.02 (0.517–31.282)

0.183

 

4th group (n = 186)

8.81 (2.386–32.554)

0.001

3.57 (0.596–21.340)

0.164

  1. aAdjusted for age, sex, body mass index, comorbidities, medications, laboratory findings, and other echocardiography findings
  2. bCombined parameter: 1st group, 1st to 3rd quartiles of E/e’ plus 3rd to 4th quartiles of ejection fraction; 2nd group, 1st to 3rd quartiles of E/e’ plus 1st to 2nd quartiles of ejection fraction; 3rd group, 4th quartile of E/e’ plus 3rd to 4th quartiles of ejection fraction; 4th group, 4th quartile of E/e’ plus 1st to 2nd quartiles of ejection fraction
  3. HR hazard ratio, CI confidence interval, E early diastolic transmitral inflow velocity, A late diastolic transmitral flow velocity, e’ early diastolic mitral annular velocity