Fig. 3

Result of group-based trajectory analysis. Trajectory of vitamin D dosage grouping from initiation of hemodialysis in the first 360 days. Trajectory model using 2 groups. Every 0.25 μg of calcitriol or alfacalcidol was defined as one dosage unit. The predicted dosage unit in each group is plotted with dotted lines. The observed proportion of individuals in each group are plotted in solid lines. After exclusion of the patients with upper 99th percentile dosage (n = 196) and application of trajectory analysis, the majority (dark black line) of vitamin D users (n = 6849) received a median of 110 (IQR 45–220) dosage units, while the remaining 326 patients (grey line) received higher cumulative dosages, median 805 (IQR 635–1080) dosage units, in the first 360 days