Table 1 Baseline characteristics of the participantsa
CKD stage III (n = 8) | Healthy controls (n = 8) | p for difference | |
|---|---|---|---|
Age (years) | 46.9 ± 12.9 | 44.5 ± 11.4 | 0.70 |
Male, no. (%) | 5 (62.5) | 5 (62.5) | 1.00 |
BMI (kg/m2) | 23.5 ± 2.8 | 25.3 ± 2.9 | 0.23 |
Smokers, no. (%) | 1 (12.5) | 0 (0) | 0.30 |
SBP (mmHg) | 134 ± 13 | 133 ± 10 | 0.87 |
DBP (mmHg) | 82 ± 11 | 78 ± 6 | 0.33 |
eGFR# (ml/min/1.73 m2) | 57 ± 17 | 100 ± 8 | < 0.01 |
IGF-1 (nmol/L) | 26.3 ± 2.8 | 27.3 ± 6.8 | 0.71 |
Serum phosphate (mmol/L) | 0.89 ± 0.16 | 1.01 ± 0.16 | 0.16 |
PTH (pmol/L) | 7.3 ± 3.1 | 4.7 ± 1.2 | 0.05 |
25(OH)D3 (nmol/L) | 70 ± 20 | 76 ± 30 | 0.69 |
cFGF23 (RU/mL) (median + IQR) | 100 (77–127) | 92 (80–105) | 0.57 |
CRP < 10 (mg/L) | 8 (100%) | 8 (100%) | n/a |
Albumin (g/L) | 38.3 ± 2.1 | 38.0 ± 2.3 | 0.82 |
α-Klotho (pg/mL) (median + IQR) | 554 (388–659) | 547 (421–711) | 0.57 |